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Co-trimoxazole - Indications, Dosage, Side Effects and Precautions

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Information about Co-trimoxazole

Generic Name : Co-trimoxazole
Pronunciation : coe try mox' a zole
Latest prescription information about Co-trimoxazole. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.8 | Therapeutic Classification : Anti- Infectives
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Trade Names/Brand Names of Co-trimoxazole

India : 

More...

International : 

Bactrim, Bactrim DS, Septra, Septra DS, Sulfatrim
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Why is Co-trimoxazole Prescribed? (Indications)

This medication is a combination of trimethoprim and sulfamethoxazole, prescribed for certain types bacterial infections. It is also used to treat traveler’s diarrhea.  It eliminates bacteria that cause various infections.

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When should Co-trimoxazole not be taken? (Contraindications)

Contraindicated in patients with anemia, hypersensitivity, during pregnancy and breast-feeding.

What is the dosage of Co-trimoxazole?

It is a fixed combination product containing sulfamethoxazole and trimethoprim in 5:1 ratio.
Adult- PO- The recommended dose is 2 tablets every 12 hours for a period of 10 to 14 days.
Child- The recommended dose is 8 mg/kg of trimethoprim and 40 mg/kg of sulfamethoxazole daily in 2 divided doses every 12 hours.

How should Co-trimoxazole be taken?

It comes as a tablet and liquid to take by mouth, with or without food.

What are the warnings and precautions for Co-trimoxazole?

• Caution should be exercised in patients with history of liver or kidney disease, asthma, severe allergies, glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (an inherited blood disease), any allergy, who are taking other medications.

• Avoid exposure to sunlight.

What are the side effects of Co-trimoxazole?

   Most Common : Nausea, vomiting and loss of appetite.
   Blood : Decrease in blood cell counts.
   Allergic : Skin inflammation, eruptions, rash, itching, redness, hives, bruising and photosensitivity.
   Gastrointestinal : Liver inflammation/damage, jaundice, hepatic necrosis, elevation in liver enzymes, inflammation of intestine/pancreas/tongue, mouth ulcer, abdominal pain and diarrhea.
   Genitourinary : Kidney failure, Blood Urea Nitrogen and absence of urination.
   Central Nervous System : Brain inflammation, convulsions, incoordination, fainting, ringing in the ear, headache, hallucinations, depression and nervousness.
   Metabolic : Low blood sugar.
   Musculoskeletal : Joint/muscle pain.
   Respiratory : Cough, shortness of breath and lung infection.
   Miscellaneous : Weakness, fatigue and sleeplessness.

What are the other precautions for Co-trimoxazole?

Avoid excess dosage.

What are the storage conditions for Co-trimoxazole?

Store it at controlled room temperature (15–25°C), protect from light.




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dulce, Philippines

i want to ask only if this medicine, same as ultramox 500mg. cause i take cotrimoxazole for the mine time,

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