Vijayaganesh Kasinathan
Written & Compiled by Pharmacist Vijayaganesh Kasinathan, B.Pharm, M.Pharm
Last Updated on Sep 26, 2017
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General Information on Chondroitin

Generic Name : Chondroitin

Pronunciation : kon-droy-tin

Latest prescription information about Chondroitin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Dietary Supplements

Trade Names/Brand Names of Chondroitin

India : 

Overview of Chondroitin

Chondroitin sulfate is a naturally occurring substance found in cartilage, a smooth elastic tissue that covers the joints in the body.
It is usually obtained from animal sources such as shark and cow cartilage.

Why is Chondroitin Prescribed? (Indications)

Chondroitin sulfate serves as an important structural component of cartilage that provides mechanical resistance against compression, shear, and friction. These cartilage act as a rubber-like padding for the joints.
Chondroitin sulfate improves the shock absorbing capacity of collagen by delivering nutrients to the cartilage and prevents the enzyme that breaks down.
It also enhances the formation of new joint cartilage.
Chondroitin sulfate is prescribed to treat osteoarthritis where the cartilage in the joints breaks down. It is often used in combination with glucosamine sulfate or glucosamine hydrochloride and manganese ascorbate.

It is also recommended in:
• Cataract surgery
• Achondroplasia
• Costochondritis
• Herniation of the spinal disc
• Urinary tract infection

When should Chondroitin not to be taken? (Contraindications)

• Hypersensitivity or known allergy to chondroitin and shellfish.
• Not recommended in asthma as the drug found to intensify the disease.
• The risk of bleeding is increased in patients with blood clotting disorders.
• To be avoided in patients suffering from prostate cancer as it may enhance the spread or relapse the cancer condition.

What is the dosage of Chondroitin?

• For Osteoarthritis :
The average oral dose is 800 – 2000 mg either as a single dose or in two to four divided doses daily for a period of three years.
Topically applied as a cream for sore joints up to 8 weeks.
Injected into the muscle either daily or twice a week for six months.

• For Urinary tract infection :
A solution containing chondroitin sulfate and hyaluronic acid inserted into the bladder once a week for first four weeks followed by once or twice a month for five months.

• Eye application :
It is used as eye solution along with hyaluronic sodium during cataract surgery.

How should Chondroitin be taken?

Chondroitin is available in capsules, tablets and powder form and to be taken orally with food.

What are the warnings and precautions for Chondroitin?

• To be used cautiously in patients with a weak immune system as chondroitin increase the risk of viral infections.
• Level of liver enzymes may be altered, therefore should be avoided in liver toxicity or liver disorders.

What are the side effects of Chondroitin?

•  Dermatological: Hair loss, skin irritation, rashes, hives, photosensitivity
•  Gastrointestinal: Nausea, heartburn, burning sensation in the stomach, vomiting
•  Cardiovascular: Congestive heart failure, changes in the heart rhythm, heart attack, hypertension, lower limb edema.
•  Central nervous system: Euphoria, Severity of existing mental illness.
•  ENT: Glaucoma, hearing problems, inflammation in the ear, eyelid edema.

What are the other precautions for Chondroitin?

Chondroitin imported from countries where ‘Mad cow disease’ is prevalent should be screened thoroughly because of the possibility of the contamination of bovine tissue with the virus.

What are the Drug Interactions of Chondroitin?

Associated risk of bleeding with anticoagulants, antiplatelet agent and non-steroidal anti-inflammatory drugs (NSAIDs).

What are the storage conditions for Chondroitin?

Store in a cool, dry place.

Last Updated : 9/26/2017

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