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Cholestyramine Resin - Indications, Dosage, Side Effects and Precautions

Cholestyramine Resin Medication Information

Learn everything you need to know about Cholestyramine Resin-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Cholestyramine Resin brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Cholestyramine Resin
Pronunciation : koe less' tir a meen
ICD Code : Y52.6 Therapeutic Classification : Antilipemics

Brand Names or Trade Names of Cholestyramine Resin

International :


Prevalite, Locholest Questran.

Why is Cholestyramine Resin Prescribed? (Indications)

This medication is a bile acid sequestrant, prescribed for high cholesterol. This medication reduces cholesterol level in the blood.

When should Cholestyramine Resin not be taken? (Contraindications)

Contraindicated in patients with intestinal obstruction and hypersensitivity.

What is the dosage of Cholestyramine Resin?

Adults - PO- Initial: 1 scoop or single-use packet (4 g anhydrous cholestyramine) daily to twice daily. Maintenance: 2 to 4 packets or scoops daily, divided into 2 doses.
Children - PO- usual dose is 240 mg/kg/day.

How should Cholestyramine Resin be taken?

It comes as a powder with dosage measurement cup or in individual dose packets to take by mouth with food.

What are the warnings and precautions for Cholestyramine Resin?

• Caution should be exercised in patients with history of heart disease, chest pain, stomach, intestinal or gallbladder disease, phenylketonuria (genetic disorder), any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• Monitor lipid and cholesterol levels and prothrombin time regularly while taking this medication.

What are the side effects of Cholestyramine Resin?

Skin - Skin irritation and rash.
Gastrointestinal - Constipation, bloating, stomach pain, gas, stomach upset, vomiting, diarrhea, loss of appetite, heartburn and indigestion.
Blood - Bleeding tendencies related to vitamin K deficiency and folic acid deficiency.
Metabolic-Nutritional - Fat-soluble vitamin deficiencies, acidity and osteoporosis.

What are the other precautions for Cholestyramine Resin?

Avoid excess dosage.

What are the storage conditions for Cholestyramine Resin?

Store it at controlled room temperature (20°-25°C).

Cholestyramine Resin : Frequently Asked Questions

Q: What are the contraindications of Cholestyramine Resin?

A: Cholestyramine Resin should not be used in patients with severe hypertriglyceridemia and complete biliary obstruction(1 Trusted Source
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Q: Does Cholestyramine resin cause constipation?

A: Constipation is a common side effect of cholestyramine that can be avoided by drinking plenty of water and eating fiber rich foods(1 Trusted Source
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Q: Is it safe to take Cholestyramine resin for long term?

A: Cholestyramine can impair the absorption of fat-soluble vitamins like vitamin K, resulting in clotting factor imbalances. Patients who are on long-term cholestyramine therapy may require fat-soluble vitamin supplementation(1 Trusted Source
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Q: Can Cholestyramine be taken with food?

A: Cholestyramine is available in the form of a chewable bar and as a powder that must be mixed with fluids or food. Cholestyramine powder can also be blended with applesauce, crushed pineapple, fruit puree, and soup(2 Trusted Source
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).

Q: When is the best time to take Cholestyramine?

A: Cholestyramine is usually taken two to four times a day. Other medications should be taken at least 1 hour before or 4 hours after cholestyramine because it can interfere with their absorption(2 Trusted Source
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).


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