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Cetuximab - Indications, Dosage, Side Effects and Precautions

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Information about Cetuximab

Generic Name : Cetuximab
Up-to-date prescription details regarding Cetuximab are provided here.

Pronunciation : seh TUX ih mab

Learn the correct pronunciation of the Cetuximab, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y43.4 Therapeutic Classification : Monoclonal antibodies

Trade Names/Brand Names of Cetuximab

International :


Erbitux

Why is Cetuximab Prescribed? (Indications)

This medication is a monoclonal antibody, prescribed for certain types of head, neck, and colorectal cancer.  It works by blocking a certain growth factor.

When should Cetuximab not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Cetuximab?

Monotherapay- The recommended initial dose is 400 mg/m2 administered as a 120-minute intravenous infusion (maximum infusion rate 10 mg/min).
With radiation therapy- Adult- IV- The recommended initial dose is 400 mg/m2 administered one week prior to initiation of a course of radiation therapy as a 120-minute intravenous infusion (maximum infusion rate 10 mg/min). Maintenance: 250mg/m2.

How should Cetuximab be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Cetuximab?

• Caution should be exercised in patients with history of abnormal blood electrolyte levels, lung or breathing problems, respiratory tract infection, heart failure, or irregular heartbeat, any allergy, who are taking other medications, children, during pregnancy and breast-feeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid exposure to sunlight.

What are the side effects of Cetuximab?

Most Common - Rash, itching, nail changes, headache, diarrhea and infections.
Serious Effects - Heart arrest, kidney failure, blood clot in lungs and skin damage.
Body as a Whole - Weakness, fever, headache, infection and chills.
Gastrointestinal - Nausea, nosebleed, diarrhea and indigestion.
Metabolic - Weight loss, dehydration, increase in liver enzyme levels.
Respiratory - Inflammation of pharynx.
Eye- Corneal ulcer.

What are the other precautions for Cetuximab?

Avoid excess dosage.

What are the storage conditions for Cetuximab?

Store it in refrigerator (2°C to 8°C). Do not freeze it.
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