This medication is a monoclonal antibody, prescribed for certain types of head, neck, and colorectal cancer. It works by blocking a certain growth factor.
Hypersensitivity.
Monotherapay-
The recommended initial dose is 400 mg/m2 administered as a 120-minute intravenous infusion (maximum infusion rate 10 mg/min).
With radiation therapy-
Adult- IV- The recommended initial dose is 400 mg/m2 administered one week prior to initiation of a course of radiation therapy as a 120-minute intravenous infusion (maximum infusion rate 10 mg/min). Maintenance: 250mg/m2.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of abnormal blood electrolyte levels, lung or breathing problems, respiratory tract infection, heart failure, or irregular heartbeat, any allergy, who are taking other medications, children, during pregnancy and breast-feeding.
• It may cause dizziness, do not drive a car or operate machinery while taking this medication.
• Avoid exposure to sunlight.
• Most Common :
Rash, itching, nail changes, headache, diarrhea and infections.
• Serious Effects :
Heart arrest, kidney failure, blood clot in lungs and skin damage.
• Body as a Whole :
Weakness, fever, headache, infection and chills.
• Gastrointestinal :
Nausea, nosebleed, diarrhea and indigestion.
• Metabolic :
Weight loss, dehydration, increase in liver enzyme levels.
• Respiratory :
Inflammation of pharynx.
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• Eye:
Corneal ulcer.
Avoid excess dosage.
Store it in refrigerator (2°C to 8°C). Do not freeze it.
Hi, I am Behrooz Farhadi master student of medical biotechnology in medical university of Tabriz from Iran. I want to know the complete DNA sequence of cetuximab for my research. Thanks a lot for your help.