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Argatroban - Indications, Dosage, Side Effects and Precautions

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Information about Argatroban

Generic Name : Argatroban
Pronunciation : ar-GA-troh-ban
Latest prescription information about Argatroban. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics
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Trade Names/Brand Names of Argatroban

International- Acova.
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Why is Argatroban Prescribed? (Indications)

This medication is an anticoagulant (thrombin inhibitor) agent prescribed for thrombosis treatment in patients with heparin-induced thrombocytopenia (low platelet levels).  

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When should Argatroban not be taken? (Contraindications)

Contraindicated in patients with severe bleeding, who are taking metronidazole, disulfiram, or heparin and hypersensitivity.

What is the dosage of Argatroban?

IV- Initial Dosage: An infusion should be started at 25 mcg/kg/min and a bolus of 350 mcg/kg over 3 to 5 minutes. It may be adjusted if needed.

How should Argatroban be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Argatroban?

• Caution should be exercised in patients with history of heart disease, blood disorder, stroke, stomach or intestinal problem, low platelet counts (thrombocytopenia), high blood pressure, liver disease, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

It may cause bleeding or bruising, avoid injury.

What are the side effects of Argatroban?

  Respiratory: Difficulty in breathing and cough.
  Heart: Low blood pressure, heart arrest, nausea and fast heart rate.
  Genitourinary: Urinary tract infection and abnormal kidney function.
  Gastrointestinal: Diarrhea, vomiting, infection and abdominal pain.
  Miscellaneous: Fever, sepsis and stroke.

What are the other precautions for Argatroban?

Avoid excess dosage.

What are the storage conditions for Argatroban?

Store it at room temperature (25C), and in an airtight container.




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