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Anidulafungin - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Anidulafungin

Generic Name : Anidulafungin
Pronunciation : a nid yoo luh FUN jin
Latest prescription information about Anidulafungin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y40.7 | Therapeutic Classification : Antifungals
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Trade Names/Brand Names of Anidulafungin

International- Eraxis.
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Why is Anidulafungin Prescribed? (Indications)

This medication is an antifungal agent, prescribed for candidemia and other forms of candida infections (intra-abdominal abscess and peritonitis) and esophageal candidiasis. It kills sensitive fungi.  It kills sensitive fungi.

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When should Anidulafungin not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Anidulafungin?

Candida infections- Loading Dose- The recommended dose is a single 200 on Day 1, followed by 100 mg daily dose thereafter.
Esophageal candidiasis- Loading Dose- The recommended dose is a single 100 mg on Day 1, followed by 50 mg daily dose thereafter.
Patients should be treated for a minimum of 14 days and for at least 7 days following resolution of symptoms.

How should Anidulafungin be taken?

IV- It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Anidulafungin?

Caution should be exercised in patients with history of liver impairment, children, bronchospasm, during pregnancy and breastfeeding.

Antifungal therapy should continue for at least 14 days after the last positive culture.

What are the side effects of Anidulafungin?

   Most Common : Rash, hives, flushing, itching, asthma, difficulty in breathing, and low blood pressure.
   Blood : Decrease in platelets.
   Heart : Heart block, abnormal heart rhythm, high and low blood pressure and flushing.
   Eye : Eye pain, vision blurred and visual disturbances.
   Gastrointestinal : Abdominal pain upper, constipation, diarrhea, indigestion, fecal incontinence, nausea and vomiting.
   General : Infusion related reaction, swelling in the extremities and rigors.
   Liver : Abnormal liver function tests and liver damage.
   Metabolic : Increase in blood minerals.
   Musculoskeletal : Back pain.
   Central Nervous System : Convulsion, dizziness, and headache.
   Respiratory : Cough.
   Skin : Redness and increased sweating.

What are the other precautions for Anidulafungin?

Avoid excess dosage.

What are the storage conditions for Anidulafungin?

Store unreconstituted vials, reconstituted solution, and diluted solution for infusion between 36 and 46F. Do not freeze. The reconstituted solution may be stored for up to 1 h; the diluted solution for infusion should be administered within 24 h.




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