This medication is an antifungal agent, prescribed for candidemia and other forms of candida infections (intra-abdominal abscess and peritonitis) and esophageal candidiasis. It kills sensitive fungi. It kills sensitive fungi.
Loading Dose- The recommended dose is a single 200 on Day 1, followed by 100 mg daily dose thereafter.
Esophageal candidiasis- Loading Dose- The recommended dose is a single 100 mg on Day 1, followed by 50 mg daily dose thereafter.
Patients should be treated for a minimum of 14 days and for at least 7 days following resolution of symptoms.
IV- It comes as a solution for injection to be administered by a healthcare provider into the vein.
• ♦ Caution should be exercised in patients with history of liver impairment, children, bronchospasm, during pregnancy and breastfeeding.
• Antifungal therapy should continue for at least 14 days after the last positive culture.
• Most Common :
Rash, hives, flushing, itching, asthma, difficulty in breathing, and low blood pressure.
• Blood : Decrease in platelets.
• Heart : Heart block, abnormal heart rhythm, high and low blood pressure and flushing.
• Eye : Eye pain, vision blurred and visual disturbances.
• Gastrointestinal : Abdominal pain upper, constipation, diarrhea, indigestion, fecal incontinence, nausea and vomiting.
• General : Infusion related reaction, swelling in the extremities and rigors.
• Liver : Abnormal liver function tests and liver damage.
• Metabolic : Increase in blood minerals.
• Musculoskeletal : Back pain.
• Central Nervous System : Convulsion, dizziness, and headache.
• Respiratory : Cough.
• Skin : Redness and increased sweating.
Avoid excess dosage.
Store unreconstituted vials, reconstituted solution, and diluted solution for infusion between 36° and 46°F. Do not freeze. The reconstituted solution may be stored for up to 1 h; the diluted solution for infusion should be administered within 24 h.
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