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Anagrelide - Indications, Dosage, Side Effects and Precautions

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Information about Anagrelide

Generic Name : Anagrelide
Pronunciation : an-AG-re-lide
Latest prescription information about Anagrelide. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics
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Trade Names/Brand Names of Anagrelide

International- Agrylin.
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Why is Anagrelide Prescribed? (Indications)

This medication is a platelet-reducing agent prescribed for thrombocythemia. This medication works by slowing the production of platelets in the body.  

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When should Anagrelide not be taken? (Contraindications)

Contraindicated in patients with severe liver disease, and hypersensitivity.

What is the dosage of Anagrelide?

Adult- The recommended starting dose is 0.5 mg qid or 1 mg bid (2 capsules of 0.5 mg twice a day) and can be increased to 4 times daily.

How should Anagrelide be taken?

It comes as a capsule to take by mouth, with or without food.

What are the warnings and precautions for Anagrelide?

• Caution should be exercised in patients with history of heart, lung, liver, or kidney problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication and get up slowly from bed.

Avoid exposure to sunlight.

It may reduce platelet counts; avoid injury or bruising.

Monitor liver function, kidney function, blood pressure, and complete blood cell counts regularly while taking this medication.

What are the side effects of Anagrelide?

   Most Common : Headache, palpitations, diarrhea, weakness, fluid retention, nausea, abdominal pain, dizziness, difficulty in breathing, flatulence, vomiting, fever, swelling in the extremities, rash, hives, chest pain, loss of appetite, fast heart rate, inflammation of pharynx, uneasiness, tingling, back pain, itching and indigestion.
   Body as a Whole : Flu symptoms, rapid weight gain, chills, pain, burning, or tingling in the hands or feet, weakness or numbness of an arm or leg and photosensitivity.
   Heart : Abnormal heart rhythm, bleeding, high blood pressure, heart disease, heart failure, postural hypotension, dilatation of blood vessels, migraine and fainting.
   Gastrointestinal : Constipation, GI distress, GI bleeding, stomach inflammation, blood in stool, mouth ulcer, eructation.
   Blood : Anemia, decrease in platelets, swelling of lymph nodes.
   Liver : Elevated liver enzymes.
   Musculoskeletal : Joint pain, muscle pain and leg cramps.
   Central Nervous System : Depression, drowsiness, seizures, confusion, sleeplessness, nervousness, and memory loss.
   Metabolic : Dehydration.
   Respiratory : Runny nose, nosebleed, respiratory disease, sinus inflammation, pneumonia, and asthma.
   Skin : Skin disease, itching and hair loss.
   Eye and ENT : Abnormal vision, ringing in the ear, visual field abnormality, double vision, cough, slow or difficult speech, ringing in the ears.
   Genitourinary : Painful urination and blood in urine.

What are the other precautions for Anagrelide?

Avoid excess dosage.

What are the storage conditions for Anagrelide?

Store it at room temperature (25C), and in an airtight container away from light and moisture.




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Comments

Akhilesh29, India

Any way to get this medicine in India?

ramesh5101, India

I also need the same medicine pls tell me the availability-RAMESH 8108164041

sachinrk, India

Can anybody plz tell me the availability of this drug - Anagrelide Hydrochloride [Agrylin] - 0.5 mg? urgently required for a pateint at Malad. ....sachin Kajrolkar, chembur, mumbai.

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