This medication is a glycoprotein, prescribed for pompe disease. It works by replacing the enzyme alfa-glucosidase in the body.
The recommended dosage is 20-mg/kg body weight administered every 2 weeks as an intravenous infusion.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of heart or lung problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
• Monitor liver function regularly while taking this medication.
• Most common:
Hives, diarrhea, vomiting, difficulty in breathing, itching, rash, throat and neck pain.
• Blood and lymphatic: Swollen glands.
• Eye and ENT: Hearing loss, ear discomfort or pain and blurred vision.
♦ • Gastrointestinal : Constipation, abdominal pain, indigestion and vomiting.
• General : Chest discomfort or pain, injection site reactions, uneasiness and swelling in the extremities.
• Immune system: Anaphylaxis, infections and stomach inflammation.
• Respiratory : Upper respiratory tract infection, procedural complications and procedural pain.
• Metabolic : Decreased potassium level in blood.
• Musculoskeletal : Muscle twitching, musculoskeletal pain and musculoskeletal stiffness or tightness.
• Central Nervous system: Drowsiness and tremor.
• Genitourinary : Kidney stones.
• Respiratory : Shortness of breath during exercise and nosebleed.
• Skin : Increased sweating.
Avoid excess dosage.
Store it in refrigerator (2° to 8°C), do not freeze it. Remove the required number of vials from the refrigerator and allow them to reach room temperature prior to reconstitution (approximately 30 minutes).
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