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Abciximab - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Abciximab

Generic Name : Abciximab
Pronunciation : ab-SIKS-ih-mab
Latest prescription information about Abciximab. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics
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Trade Names/Brand Names of Abciximab

India : 

International : 

Reopro
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Why is Abciximab Prescribed? (Indications)

Abciximab blocks the sticking of platelets together and protects the arteries by reducing the formation of thrombus or blood clot.

It is used mainly during coronary artery procedures such as angioplasty with or without stent placement to prevent complications of the heart.  
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When should Abciximab not be taken? (Contraindications)

Active bleeding
Recent bleeding due to surgery, bleeding from the digestive tract or from other sites, stroke due to a bleed
Increased risk for bleeding due to bleeding/clotting disorders, very high blood pressure, brain tumor, etc.
Allergic reaction

What is the dosage of Abciximab?

Before procedures on the heart like angioplasty. It is given in a dose of 0.25mg/kg into the vein 10-60 minutes before the procedure, followed by an infusion of 0.125 g/kg/min up to a maximum of 10 g/min for 12 hours .
Treatment of heart attack, stroke due to a blood clot

How should Abciximab be taken?

Injected into the vein by a healthcare provider.

What are the warnings and precautions for Abciximab?


Platelet counts, bleeding and clotting times should be monitored before and during treatment
May cause excess bleeding when administered with other drug with bleeding as side effects. e.g. aspirin, warfarin, t-PA (tissue plasminogen activator) which is used to break clots

What are the other precautions for Abciximab?

As tendency to bleed is possible, using of a soft toothbrush or electric razor is advised.
In case of overdose, call a poison control center or an emergency center for an appropriate treatment.

What are the storage conditions for Abciximab?

Store at 2 to 8C. Discard any unused portion left in the vial.
Last Updated : Jul 2018



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