In Vitiligo, melanin is either destroyed or not produced. The exact cause of Vitiligo is not known yet. A number of theories exist. The most widely accepted view is that Vitiligo is an autoimmune disease, i.e. one in which the personís immune system attacks the organs and tissues of the body. Heredity may be a factor since Vitiligo runs in certain families. However, only 5 to 7 percent of children will get Vitiligo even if a parent has it.
Sometimes, a single event, such as sunburn or emotional distress, can trigger the condition.
The main sign of Vitiligo is pigment loss. Vitiligo causes milky-white patches (depigmentation) on skin. The diagnosis of Vitiligo is made based on a physical examination, medical history, and laboratory tests. Medical treatment for Vitiligo is not always necessary. Treatment includes topical corticosteroids, topical immunomodulators (e.g., tacrolimus), phototherapy etc. Surgical modalities are also available.
Latest Publications and Research on VitiligoImmune toxicities and long remission duration after ipilimumab therapy for metastatic melanoma: two illustrative cases. - Published by PubMed
Association between FOXP3 polymorphisms and vitiligo in a Han Chinese population. - Published by PubMed
Dermal Mesenchymal Stem Cells (DMSCs) Inhibit Skin-Homing CD8+ T Cell Activity, a Determining Factor of Vitiligo Patients' Autologous Melanocytes Transplantation Efficiency. - Published by PubMed
Decreased regulatory t-cells and cd4(+) /cd8(+) ratio correlate with disease onset and progression in patients with generalized vitiligo. - Published by PubMed
Vitiligo and Allergic Complications from Orthopaedic Joint Implants: The Role of Benzoyl Peroxide. - Published by PubMed