Chikungunya virus (CHIKV) is an arbovirus i.e. it is an arthropod borne virus and is a member of the genus Alphavirus, in the family Togaviridae.
The first outbreak of the disease was seen in the year 1952, in the Makonde plateau, along the border between Tanzania and Mozambique. The disease occurs predominantly in Africa, Asia and the Indian subcontinent.
The disease was first described by Marion Robinson and W.H.R. Lumsden in 1955. The name ‘Chikungunya’ is derived from a root verb in the Kimakonde language which means –‘that which bends up’ and is in reference to the stooped posture that develops due to the arthritic symptoms of the disease.
Since the disease shares some clinical signs with dengue fever, it can be misdiagnosed in areas where dengue is common.
There is no cure for the disease. It is a self-limiting infection and most patients recover fully. No deaths, neuro-invasive cases or hemorrhagic cases related to chikungunya infection have been conclusively documented in the scientific literature.
Treatment of chikungunya is focused on relieving the symptoms.
Latest Publications and Research on ChikungunyaCharacterization of chikungunya virus infection of a human keratinocyte cell line: Role of mosquito salivary gland protein in suppressing the host immune response. - Published by PubMed
Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization. - Published by PubMed
Public health significance of invasive mosquitoes in Europe. - Published by PubMed
The Role of Innate versus Adaptive Immune Responses in a Mouse Model of O'Nyong-Nyong Virus Infection. - Published by PubMed
A Wolbachia wMel Transinfection in Aedes albopictus Is Not Detrimental to Host Fitness and Inhibits Chikungunya Virus. - Published by PubMed