The causes of aortic stenosis
► Bicuspid and Other Congenitally Abnormal Aortic Valves
A Normal aortic valve has three thin leaflets called cusps (tricuspid). About 1% of the population is born with a bicuspid aortic valve, i.e. with only two cusps in the valve. There exists a male preponderance. Although this abnormality does not usually cause symptoms at birth these valves tend to deteriorate with age. By the time these individuals reach their 40s, 50s, and 60s aortic stenosis may develop.
Congenital aortic stenosis from a unicuspid, bicuspid, or even abnormal tricuspid valve may cause symptoms during childhood and necessitates rectification by adolescence.
► Tricuspid Aortic Valve Stenosis
A previously normal tricuspid aortic valve can also develop thickening and calcification. Stenosis and calcifications were formerly considered to be degenerative processes.
Currents concepts are that this type of aortic stenosis arises from an active inflammatory process.
► Rheumatic Heart Disease
Scarring of the aortic valve due to rheumatic fever as a child or young adult is a rare cause in developed countries. Unfortunately rheumatic heart disease is still rampant in the developing nations.
Latest Publications and Research on Aortic Valve StenosisImpact of Concomitant Coronary Artery Disease on Atherosclerotic Plaques in the Aortic Arch in Patients With Severe Aortic Stenosis. - Published by PubMed
Antithrombotic Treatment in Transcatheter Aortic Valve Implantation: Insights for Cerebrovascular and Bleeding Events. - Published by PubMed
The Transaortic Approach for Transcatheter Aortic Valve Replacement: Initial Clinical Experience in the United States. - Published by PubMed
Asymptomatic Severe Aortic Stenosis with Left Ventricular Dysfunction: Watchful Waiting or Valve Replacement? - Published by PubMed
Monitoring of procedures: peri-interventional echo assessment for transcatheter aortic valve implantation. - Published by PubMed