This medication is an anthracycline agent, prescribed for acute non-lymphocytic leukaemia. It has a selective inhibitory effect on the synthesis of RNA in the cells
Contraindicated in patients with severe heart disease, bone marrow depression, and hypersensitivity.
Adult: IV- Initial: 175-300 mg/m2, divided over 3-7 consecutive days. Maintenance: 25-100 mg/m2 3-4 weekly.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of liver or kidney impairment, radiation-induced heart attack, and use of radiotherapy, during pregnancy and breastfeeding.
• Monitor complete blood counts, liver function, uric acid level in blood regularly while taking this medication.
• Severe Effects :
Heart damage and bone marrow suppression.
• Gastrointestinal : Nausea, vomiting, irritant to tissue, sore mouth, diarrhea, and gastrointestinal tract inflammation.
• Blood : Anemia, bone-marrow suppression.
• Skin : Hair loss.
• Liver: Hepatic dysfunction.
• Genitourinary : Blood in urine.
Avoid live vaccination during the treatment period.
Avoid excess dosage.
IV Inj: Store at room temperature (20 to 25°C). Protect from sunlight. IV Inj (reconstituted solution): Store below 40°C. Use within 24 hours if kept at room temperature.
Urinary retention is a condition where a person is unable to voluntarily empty the urinary bladder ...
Hashimoto's thyroiditis is an autoimmune disorder of the thyroid causing hypothyroidism. Synthetic ...
Strokes occur when blood flow to an area of the brain is cut off. It is imperitive to detect the ...View All