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Generic Name : Aclarubicin
Pronunciation : äk lá rü ' bï sïn
Trade Name(s):
India- Klasinomycin. International- Aclacinon. This medication is an anthracycline agent, prescribed for acute non-lymphocytic leukaemia. When it is not to be taken (Contraindications):
When it is to be taken : Adult: IV- Initial: 175-300 mg/m2, divided over 3-7 consecutive days. Maintenance: 25-100 mg/m2 3-4 weekly. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein. Special Instruction : * Caution should be exercised in patients with history of liver or kidney impairment, radiation-induced heart attack, and use of radiotherapy, during pregnancy and breastfeeding. * Monitor complete blood counts, liver function, uric acid level in blood regularly while taking this medication. Side Effects : Severe Effects - Heart damage and bone marrow suppression. Gastrointestinal - Nausea, vomiting, diarrhea, abnormal liver function and gastrointestinal tract inflammation. Blood - Decrease in blood cells. Skin - Hair loss. Genitourinary - Blood in urine. * Avoid live vaccination during the treatment period. * Avoid excess dosage. Storage Conditions : IV Inj: Store at room temperature (20 to 25°C). Protect from sunlight. IV Inj (reconstituted solution): Store below 40°C. Use within 24 hours if kept at room temperature. |
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