Aclarubicin - Drug Information

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General Information on Aclarubicin

Generic Name : Aclarubicin

Pronunciation : k l r ' b sn

Latest prescription information about Aclarubicin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.3 | Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Aclarubicin

India : 

International : 

Aclacinon, Aclacin, Aclacinomycine, Aclaplastin, Jaclacin

Why is Aclarubicin Prescribed? (Indications)

This medication is an anthracycline agent, prescribed for acute non-lymphocytic leukaemia. It has a selective inhibitory effect on the synthesis of RNA in the cells

When should Aclarubicin not to be taken? (Contraindications)

Contraindicated in patients with severe heart disease, bone marrow depression, and hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Aclarubicin?

Adult: IV- Initial: 175-300 mg/m2, divided over 3-7 consecutive days. Maintenance: 25-100 mg/m2 3-4 weekly.

How should Aclarubicin be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Aclarubicin?

Caution should be exercised in patients with history of liver or kidney impairment, radiation-induced heart attack, and use of radiotherapy, during pregnancy and breastfeeding.
Monitor complete blood counts, liver function, uric acid level in blood regularly while taking this medication.

What are the side effects of Aclarubicin?

  Severe Effects : Heart damage and bone marrow suppression.
   Gastrointestinal : Nausea, vomiting, irritant to tissue, sore mouth, diarrhea, and gastrointestinal tract inflammation.
   Blood : Anemia, bone-marrow suppression.
   Skin : Hair loss.
  Liver: Hepatic dysfunction.
   Genitourinary : Blood in urine.

What are the other precautions for Aclarubicin?

Avoid live vaccination during the treatment period.
Avoid excess dosage.

What are the storage conditions of Aclarubicin?

IV Inj: Store at room temperature (20 to 25C). Protect from sunlight. IV Inj (reconstituted solution): Store below 40C. Use within 24 hours if kept at room temperature.


Schedule : H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

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