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Aclarubicin - Indications, Dosage, Side Effects and Precautions

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Information about Aclarubicin

Generic Name : Aclarubicin
Pronunciation : k l r ' b sn
Latest prescription information about Aclarubicin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.3 | Therapeutic Classification : Chemotherapy
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Trade Names/Brand Names of Aclarubicin

India : 

International : 

Aclacinon, Aclacin, Aclacinomycine, Aclaplastin, Jaclacin
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Why is Aclarubicin Prescribed? (Indications)

Aclarubicin or aclacinomycin A is used to treat acute non lymphocytic leukemia, a cancer of the blood and bone marrow. It is an oligosaccharide anthracycline agent produced by a soil bacterium called Streptomyces galilaeus and has powerful anticancer activity. 

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When should Aclarubicin not be taken? (Contraindications)

Contraindicated in patients with severe heart disease, bone marrow depression, and hypersensitivity.

What is the dosage of Aclarubicin?

Adult: IV- Initial: 175-300 mg/m2, divided over 3-7 consecutive days. Maintenance: 25-100 mg/m2 3-4 weekly.

How should Aclarubicin be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Aclarubicin?

• Caution should be exercised in patients with history of liver or kidney impairment, radiation-induced heart attack, and use of radiotherapy, during pregnancy and breastfeeding.

Monitor complete blood counts, liver function, uric acid level in blood regularly while taking this medication.

What are the side effects of Aclarubicin?

  Severe Effects : Heart damage and bone marrow suppression.
   Gastrointestinal : Nausea, vomiting, irritant to tissue, sore mouth, diarrhea, and gastrointestinal tract inflammation.
   Blood : Anemia, bone-marrow suppression.
   Skin : Hair loss.
  Liver: Hepatic dysfunction.
   Genitourinary : Blood in urine.

What are the other precautions for Aclarubicin?

Avoid live vaccination during the treatment period.
Avoid excess dosage.

What are the storage conditions for Aclarubicin?

IV Inj: Store at room temperature (20 to 25C). Protect from sunlight. IV Inj (reconstituted solution): Store below 40C. Use within 24 hours if kept at room temperature.


Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
Last Updated : Jul 2018



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