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Acute Myeloid Leukemia

Last Updated on Jun 22, 2020
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Nomenclature: Acute Myeloid Leukemia, Acute Myelogenous Leukemia, AML.


Acute myeloid Leukemia, more popularly known by its abbreviated form - AML, is a fast- evolving leukemia that affects both children and adults alike.

Acute Myeloid Leukemic cells under Microscope

Acute Myeloid

The word 'leukemia' means 'white blood,' and is used to indicate the high white blood cell counts of the disease.

Leukemia is a cancer that begins in the inner part of the bone marrow and moves quickly into the blood from where it spreads to other parts such as the spleen, lymph nodes, liver, central nervous system and to the other organs of the body. There are two forms of myeloid leukemia chronic and acute. The term 'Chronic' refers to slowly evolving form of myeloid leukemia that may take years to progress. The 'acute' variety, on the other hand, advances in a quick manner. 'Myeloid' refers to the type of WBC that is affected. Leukemia was first recognized 150 years ago, and since then has been intensely researched and studied. The treatment of leukemia over the years has seen remarkable triumphs, frustrations and failures. Dr.Donald Pinkel, St. Jude Children's Research Hospital, USA, sums it up as follows:

"The value of history is not just in savoring the past, but in appreciating how it illuminates the present and guides us into the future. Several lessons can be learned from the study of the history of leukemia, particularly childhood leukemia. One is the importance of heeding new facts and listening to new ideas and hypotheses. At each point in the history of leukemia there have been instances of lost time and opportunity because of unreasoned resistance to innovation. It is important for physicians and scientists to be open to new thinking that challenges conventional wisdom and ways.


Normally the bone marrow produces immature stem cells that grow and differentiate into the three blood cells type the Red Blood Cells (RBC), the White Blood Cells (WBC) and Platelets. These blood cells vary in their morphology and function. The RBCs carry oxygen and other nutrients to the different body tissues; the WBCs fight off infections and diseases while the platelets are responsible for blood coagulation.

Blood Cell

In leukemia, a single WBC stem cell becomes abnormal and undergoes uncontrolled proliferation. These leukemic cells can be found in the blood and they course through the body, causing enlargement of the spleen, liver and other organs.

What is New in Acute Myeloid Leukemia?

1. Myeloid Leukemia Can Now be Put To Stop by Blocking Its Growth Factor

A new role of a circadian clock protein has been found to assist in the development of acute myeloid leukemia (AML), finds a new study. SHARP1 protein has been found, this protein usually is responsible for circadian rhythm in the body but is now linked to acute myeloid leukemia development.

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Latest Publications and Research on Acute Myeloid Leukemia

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my friend surfing with acute myeloblastic leukemia with maturation. Now he going on chemotherapy. He is on my 2nd session[0, 1 ,2]. Still two more session as per the doctor. Also Doctor's told good progress. I want to know what type of food will add more value to get more immunity. Please give some suggestion on food from nature.


Hi.. i am 23 years old diagnose with AML last October 2012 and currently receiving chemotherapy. i am on my 2nd session and my doctor said i will have another session this december. id like to know when they say 5 years survival does that mean i only have 5years left eventhough i take my chemotherapy?


No, that only means that they certify that your cancer is cured only after 5 years, till then they monitor and see that it doesn't relapse by then.


78 years aged mother suffering from lukemia pls tell me about the effective medicine and tell me about the chancec or not for recovery.. and which medicine are good for the acute lukemia pls write some medicines name for the recovery for the patitent


plz take your mother to cancer hospital.the medicine is depends up on the type of leukemia.


I have Acute Leukemia[AML] cancer to my sister. Her age is 25 years. In recent test reports Blast are about 80%. Can you please tell me how i can proceed to cure my sister.


Hello.i just read about AML and i am satisfied with the information providede. Though i have one small enquiry; Anthracycline has been listed as one of the drugs given during Chemotherapy that may cause AML in the future and yet it has been listed as a drug for treating AML. Doess it mean that you are at risk of contracting AML again? I will apprecite your assistance on this qustion..


Anthracyclines have been found to produce AML in patients who underwent treatment for breast cancer and Hodgkin's lymphoma, especially when used with other anticancer drugs and in high doses. Currently anthracyclines are very effective in AML, and the risk of them causing AML are small, hence they are used in AML.

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