Medindia LOGIN REGISTER
Medindia

Acute Myeloid Leukemia - Prognosis

AML - Prognosis

Acute Myeloid Leukemia can be controlled and sometimes cured. Its prognosis depends on a variety of factors that is patient-specific.

AML can be kept in remission for a long period of time or even cured in some adults. Depending on certain factors such as, the characteristics of the leukemia cells. Some patients have a better prognosis in comparison to others.

  • Adults below 65 years 5-year survival rate - about 33%
  • Adults above 65 years - 4% only
  • Many people who live much longer than the average 5 years

The prognosis of a patient depends on the following factors:

Advertisement
  • Patient’s age and race - Younger patients and Caucasians have a good prognosis, while patients older than 60 years and patients of African- American descent have a poor prognosis
  • Subtype of AML - M3 has good prognosis while the M7 type has poor prognosis
  • Patient’s response to therapy
  • AML that follows myelodysplastic syndrome or myeloproliferative diseases has a poor prognosis
  • Elevated lactate dehydrogenase levels has a poor prognosis
  • Cytogenetics plays an important role in predicting the progress of an AML patient as represented in the table below:
Chromosomal Aberration

Advertisement
Recommended Reading