About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Weight-loss Surgery may Work Better for Teens Than Adults

by Hannah Joy on May 17, 2019 at 12:11 PM
Font : A-A+

Weight-loss Surgery may Work Better for Teens Than Adults

Teens who had gastric bypass surgery were more likely to be exempted from developing both type 2 diabetes and hypertension (high blood pressure), reveals a new study.

Results are from an NIH-funded study comparing outcomes in the two groups five years after surgery. Previously, no treatment has shown longer-term effectiveness at reversing type 2 diabetes in youth, which tends to advance more quickly than in adults.

Advertisement


Scientists evaluated 161 teens and 396 adults who underwent this surgery at clinical centers participating in Teen-LABS (Teen-Longitudinal Assessment of Bariatric Surgery) and its adult counterpart, LABS.

Teens in the study were under 19 years old at the time of surgery, and adults in the study reported having obesity by age 18. Teen-LABS clinical centers had specialized experience in the surgical evaluation and management of young people with severe obesity, and both studies were funded primarily by NIH's National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
Advertisement

The results were published in The New England Journal of Medicine.

"Obesity increases the risk for type 2 diabetes and cardiovascular diseases, and these conditions can be more difficult to manage in young people," said Mary Evans, Ph.D., a study author and program director in the NIDDK Division of Digestive Diseases and Nutrition. "We found earlier bariatric surgery in carefully selected youth may have greater benefits compared to waiting until later in life."

Key findings of the research include:
  • Overall weight loss percentage was not different between the groups. Teens lost 26% of their bodyweight and adults lost 29 percent at five years after surgery.
  • Type 2 diabetes declined in both groups, but teens with type 2 diabetes before surgery were 27 percent more likely than adults to have controlled blood glucose (blood sugar) without the use of diabetes medications.
  • No teens in the group needed diabetes medications after surgery, compared to 88 percent of teens before surgery. 79 percent of adults used diabetes medications before surgery, and 26 percent used diabetes medications five years later.
  • Before surgery, 57 percent of teens and 68 percent of adults used blood pressure medications. Five years after surgery, 11 percent of teens and 33 percent of adults used blood pressure medications.
  • Among those with high blood pressure before surgery, teens were 51 percent more likely than adults to no longer have high blood pressure or take blood pressure medication.
  • However, teens were more likely to have increased risks in other areas, including a need for subsequent abdominal surgeries, most commonly gall bladder removal. Teens were also more likely to have low iron and vitamin D levels, potentially because teens may be less likely to take enough vitamin and mineral supplements after surgery.

    There was a similar death rate for both teens and adults five years after surgery, including two people from the teen group who died from overdose. There is an overall increasing trend of drug overdose deaths in the U.S., and a previous LABS study found an increased risk of substance and alcohol use disorders after bariatric surgery in adults.

    "Although there are risks associated with bariatric surgery, this study demonstrates that, for many young people, the benefits likely outweigh the risks," said Thomas Inge, M.D., Ph.D., the study's first author from Children's Hospital Colorado. "Sufficient vitamin and mineral supplementation, along with continued medical care, can help mitigate some of these risks."

    These results build on earlier research related to the benefits, risks, and timing of bariatric surgery to aid in weight management. Obesity affects more than one in three adults and about 17% of American children and teens. Obesity increases risk for type 2 diabetes, heart and kidney diseases, some types of cancer, and other health conditions.

    "Type 2 diabetes in youth has been a growing problem without a solution, hitting young adults with serious health conditions when they should be in the prime of their lives. This study demonstrates that bariatric surgery may provide an effective treatment, though not one without risks," said NIDDK Director Dr. Griffin P. Rodgers. "We hope future research continues to shed light on the best timing and the most effective treatments for all people with weight-related conditions."



    Source: Eurekalert
    Advertisement

    Advertisement
    Advertisement

    Latest Obesity News

     Diabesity: Discovering the Connecting Link Between Obesity and Diabetes
    Researchers examine the role of unknown protein NOTCH2-associated receptor2 (MINAR2) in obesity and diabetes using generated Minar2 knockout (KO) mice.
    Beyond the Scalpel: Study Debunks Weight Loss Expectations Post Surgery
    Study reports that body contouring after bariatric surgery does not contribute to long-term weight loss in patients with massive weight loss.
    Revamping Weight Loss Solutions Using Anti-Obesity Medication
    Recently FDA-approved drug semaglutide has proven as a highly effective anti-obesity medication showcasing remarkable weight loss benefits.
    Exploring Microbiota's Influence on Weight Development
    Gut bacteria profile and abundance in toddlers can serve as a predictive factor for their body mass index (BMI) at age 5, irrespective of premature birth status.
    What Are the Consequences of Uncontrolled Hunger in Teenagers Living With Obesity?
    Obese individuals were found to have weaker appetite regulation, with factors that inhibit eating behavior.
    View All
    This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
    ×

    Weight-loss Surgery may Work Better for Teens Than Adults Personalised Printable Document (PDF)

    Please complete this form and we'll send you a personalised information that is requested

    You may use this for your own reference or forward it to your friends.

    Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

    Name *

    Email Address *

    Country *

    Areas of Interests