About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Treatment Options for Anti-NMDA Receptor Encephalitis Compared

by Chrisy Ngilneii on March 15, 2018 at 11:13 PM
Font : A-A+

Treatment Options for Anti-NMDA Receptor Encephalitis Compared

Treatment options for anti-NMDA receptor encephalitis in male patients without tumor are compared to see superiority of efficacy. The study finds that all treatment options yield an equal result.

Anti-NMDA receptor encephalitis is an acute disease occurring when antibodies produced by the body's own immune system attack N-methyl-D-aspartate (NMDA) receptors in the brain. Recovery from this disease occurs as a multistage process, which can take from several months to several years after disease onset. Some anti-NMDA receptor encephalitis patients have detectable tumors, and they had significant improvement after tumor resection. It reveals that this tumor is the cause of this disorder. For other patients, the cause is often unknown. There are several reports indicating that it is related to vaccination.

Advertisement


The treatments for this disorder include first-line immunotherapies: steroids, intravenous immunoglobulin (IVIG) or plasmapheresis (or plasma exchange); and second-line immunotherapy such as rituximab or cyclophosphamide. In addition, it is suggested that tumors be resected from these patients. The choice of treatments may be a potential factor that facilitates an early recovery from anti-NMDA receptor encephalitis. Studies on the efficacies of treatments for anti-NMDA receptor encephalitis have revealed that patients receiving at least two different forms of therapy may have higher efficacy rates than patients receiving a single form of therapy.

The results of this comparison reveal that it is possible to find the effective treatment strategy for a specific group of patients although this treatment strategy may not always be effective for the patients that are not in this specific group. Most studies for the anti-NMDA receptor encephalitis provided an overview statistical result for this disease but did not focus on any patient-specific treatment discussion.

This study can provide a patient-specific treatment strategy since the efficacy rate of plasmapheresis (or plasma exchange) is not inferior to those of intravenous immunoglobulin and rituximab (or cyclophosphamide) for male patients without tumor.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Coffee May Help You Fight Endometrial Cancer
Fermented Skin Care
Television Binge-Watching May Boost the Risk of Deadly Blood Clots
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
What You Should Know about Japanese Encephalitis Meningitis Cat Scratch Disease Encephalitis 

Recommended Reading
Autoimmune Disorders
Autoimmune disorders occur when the immune system fails to recognize the body as 'self' and attacks ...
Autoimmune Hepatitis
Autoimmune hepatitis is a type of chronic liver inflammation that responds well to ......
Zika Fever
Zika virus is transmitted to humans by infected mosquitoes which causes mild fever with ......
Lupus Nephritis
Lupus nephritis occurs in 60% of patients with systemic lupus erythematosus (SLE) and is classified ...
Cat Scratch Disease
Cat scratch disease (CSD) is a self-limiting infection that spreads through contact with cats....
Encephalitis
Encephalitis is the inflammation of the brain, mostly caused by viruses. Though rare, it is a seriou...
Meningitis
Meninges are the three layers of membrane that cover the brain and infection of the cerebrospinal fl...
What You Should Know about Japanese Encephalitis
Japanese encephalitis is a mosquito borne viral disease associated with inflammation of the brain....

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
CONSULT A DOCTOR
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)