Researchers at the University of Notre Dame have gained significant insights into the process whereby the malaria parasite Plasmodium falciparum develops drug resistance.
Michael Ferdig, a biologist at the University of Notre Dame, pint out that the development of Plasmodium falciparum in the blood is driven by a number of different genes expressed at different times and at different levels.
Malaria
Malaria is caused by a parasite that enters blood through the bite of an infected mosquito. It is characterized by fever, vomiting, shivering, sweating and other symptoms.
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The researcher revealed that combining classical genetics with cutting-edge genomic methods enabled his team to illuminate previously unrecognised transcriptional complexity and variation in Plasmodium falciparum, and possibly master regulators within large copy number variants that contribute to the drug-resistant phenomena in malaria parasites.
He believes that uncovering the genetic "architecture" of numerous drug responses, and identifying key regulators that control such responses, may help map new approaches to conquering drug resistant malarial genes.
His findings have been reported in two research papers separately published in the journals PLoS Biology and PLoS Genetics.
Source: ANI
SRM
His findings have been reported in two research papers separately published in the journals PLoS Biology and PLoS Genetics.
Source: ANI
SRM
Newer Diagnostic tests for Malaria
To aid in rapid and precise diagnosis of malaria, recent advance in newer diagnostic modalities have surfaced. The principal manifestations of cerebral malaria are seizures and impaired consciousness.
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 Malaria Treatment - Home RemedyHome remedies offer you herbal and natural method to treat Malaria effectively. It also explains the preparation, using basic household ingredients and dosage to get rid of the ailment | Advertisement
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