In British children, an association between low vitamin D status and non-alcoholic fatty liver disease (NAFLD) has been discovered by scientists.
The research, conducted by the King's College Hospital Paediatric Liver Centre and the University of Surrey's School of Biosciences and Medicine, and funded by the Children's Liver Disease Foundation retrospectively analysed the medical records of 120 paediatric patients with NAFLD.
Alcoholic Liver Disease
Encyclopedia section of medindia gives general information about Alcoholic Liver Disease.
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The findings could carry significant implications for UK clinicians in light of the nation's rising number of childhood NAFLD cases. High levels of vitamin D deficiency and increasing numbers of rickets cases are thought to be due to the obesity epidemic, more children increasingly choosing to play indoors rather than outside and the excessive use of sun-creams.
EASL's Educational Councillor Professor Jean-Francois Dufour of the University Clinic for Visceral Surgery and Medicine, University of Bern, Switzerland said: "The data support recent research that revealed an association between low vitamin D status and incidence of NAFLD and is an important development in helping clinicians better understand the growing rate of NAFLD in children throughout the western world."
![Sunlight: An Important Source of Vitamin D]( "Sunlight: An Important Source of Vitamin D")
Vitamin D is an essential vitamin necessary for the development of bones. Sunlight helps the body to produce vitamin D. Vitamin D deficiency results in rickets in children and osteomalacia in adults.
"Identifying a gene that impacts or alters the disease is a step in the right direction and could potentially lead to the development of new treatments or diagnostic techniques to address this growing issue," Professor Dufour continued. "More research into this field is warranted and I look forward to seeing future developments over time."
NAFLD is the term used to describe fat build-up in liver cells in people who do not drink alcohol excessively.[ii] NAFLD is rapidly becoming the most common liver disease worldwide and is the most common persistent liver disorder in western countries and is estimated to affect up to 10% of Europe's paediatric population.[iii] The disease has an estimated overall prevalence of 20% to 30% across Europe.[iv],[v]
Patients were found to have low vitamin D blood levels throughout the entire year, not just in the winter months, plus the majority of samples were found to be deficient or insufficient in vitamin D status compared to national UK and US health standards. The study also detected a variant of the NADSYN1 gene which was associated with NAFLD severity in patients.
Source: Eurekalert
Sunlight: An Important Source of Vitamin D
Vitamin D is an essential vitamin necessary for the development of bones. Sunlight helps the body to produce vitamin D. Vitamin D deficiency results in rickets in children and osteomalacia in adults.
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"Identifying a gene that impacts or alters the disease is a step in the right direction and could potentially lead to the development of new treatments or diagnostic techniques to address this growing issue," Professor Dufour continued. "More research into this field is warranted and I look forward to seeing future developments over time."
NAFLD is the term used to describe fat build-up in liver cells in people who do not drink alcohol excessively.[ii] NAFLD is rapidly becoming the most common liver disease worldwide and is the most common persistent liver disorder in western countries and is estimated to affect up to 10% of Europe's paediatric population.[iii] The disease has an estimated overall prevalence of 20% to 30% across Europe.[iv],[v]
Patients were found to have low vitamin D blood levels throughout the entire year, not just in the winter months, plus the majority of samples were found to be deficient or insufficient in vitamin D status compared to national UK and US health standards. The study also detected a variant of the NADSYN1 gene which was associated with NAFLD severity in patients.
Source: Eurekalert
Quiz on Liver
How many of us know that the liver is a vital organ the size of an American Football? To understand more about the liver and its functions spend a few minutes taking part in this quiz.
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 Reason for the Surge of Vitamin D Deficiency DiagnosesPhysicians are ordering vitamin D deficiency screening tests for preventive care purposes instead of taking measures after people develop conditions caused by decreased bone density. | Advertisement
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