A new immune cell that intensifies rheumatoid arthritis has been discovered by a team of researchers from Japan.
Rheumatoid arthritis is an inflammatory disorder that mainly affects joints and occurs when excessive immune response destroys bone.
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According to the researchers, the new cell is created when the cell that originally controlled the excessive immune reactions mutates, the Japan times reported.
The study on mice found that it later powerfully promotes the activities of osteoclast, a cell that destroys bones.
The team, which included University of Tokyo visiting researcher Noriko Komatsu and professor Hiroshi Takayanagi, revealed that the same mutation is believed to happen in human arthritis patients.
![Quiz on Arthritis]( "Quiz on Arthritis")
Do you know that there are more than 100 types of arthritis? If you think that only old people suffer from arthritis, take this intriguing quiz to get your facts on arthritis.
Bones and cartilage in joints are usually shielded by synovial membrane and fluid secreted from it. In arthritis patients, abnormal growth of cells in the membrane causes inflammation.
The team also found that interleukin-6 released by cells, in the membrane that causes inflammation, triggers the mutation.
The study is published in journal Nature Medicine.
Source: ANI
The team, which included University of Tokyo visiting researcher Noriko Komatsu and professor Hiroshi Takayanagi, revealed that the same mutation is believed to happen in human arthritis patients.
Quiz on Arthritis
Do you know that there are more than 100 types of arthritis? If you think that only old people suffer from arthritis, take this intriguing quiz to get your facts on arthritis.
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Bones and cartilage in joints are usually shielded by synovial membrane and fluid secreted from it. In arthritis patients, abnormal growth of cells in the membrane causes inflammation.
The team also found that interleukin-6 released by cells, in the membrane that causes inflammation, triggers the mutation.
The study is published in journal Nature Medicine.
Source: ANI
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 Genetic Variation in Mice Exacerbates Inflammatory ArthritisResearchers at University of Utah have discovered a naturally occurring genetic variation in mice that predisposes carriers toward developing severe, inflammatory arthritis. | Advertisement
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