About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Researchers Identify Novel Chemical Compound That Targets Drug-Resistant Bacteria

by Aruna on September 30, 2009 at 12:49 PM
Font : A-A+

Researchers Identify Novel Chemical Compound That Targets Drug-Resistant Bacteria

In a breakthrough discovery, researchers at McMaster University have revealed an ideal starting point to develop new interventions for resistant infections.

Led by Eric Brown, the researchers have identified a novel chemical compound that targets drug-resistant bacteria in a different way from existing antibiotics.

Advertisement

The discovery could lead to new treatments to overcome antibiotic resistance in certain types of microorganisms.

"Everyone reads the headlines about drug-resistant bugs, it's a big problem," Nature quoted Brown, who holds the Canada Research Chair in Antimicrobial Research, as saying.
Advertisement

"Really what we're trying to do is understand whether or not there are new ways to tackle this problem," he added.

The research team, which included biochemists and chemists from McMaster University, used high-throughput screening to uncover the new class of chemical.

With the new approach scientists could look for small molecules that kill bacteria as well as examine the molecular mechanisms and pathways they exploit.

Existing antibiotics destroy bacteria by blocking production of its cell wall, DNA or protein.

The newly discovered compound, MAC13243, is directed at blocking a particular step in the development of the bacteria's cell surface, which until now has not been recognized as a target for antibiotics.

"We're excited about finding a new probe of a relatively uncharted part of bacterial physiology. It's a new way of thinking about the problem. Who knows, could this chemical become a drug? Anything's possible. But at the very least we've advanced the field and created some tools that people can use now to try to better understand this pathway," said Brown.

The findings of the study have been published in the journal Nature Chemical Biology.

Source: ANI
ARU
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Printed Temperature Sensors help with Continuous Temperature Monitoring
Health Benefits of Giloy
Breast Cancer Awareness Month 2021 - It's time to RISE
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Shigellosis 

Recommended Reading
Antibiotic-Resistant Germs Claim Every Nook On Earth
According to new research, you may have no place on earth to hide from germs dangerously resistant ....
Slow-Growing TB Bacteria May Help In New Drug Development
The discovery of a large number of slow-growing Mycobacterium tuberculosis bacteria, which cause ......
Shigellosis
Shigellosis or Bacillary Dysentery is a common cause of gastro-enteritis worldwide and can cause blo...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use