Massachusetts General Hospital researchers have developed a two-step process that uses a chemical reaction to make live cancer cells light up quickly and safely.
This attains significance because scientists generally label cells with colored or glowing chemicals to observe how basic cellular activities differ between healthy and cancerous cells, but existing techniques are either too slow or too toxic to perform on live cells.
Study Sheds Light on Cancer Cells
In order to understand how basic cellular activities differ between healthy and cancerous cells, scientists label cells with coloured or glowing chemicals.
Advertisement
Under the novel process, chemically modified antibodies first home in on cancer cells, and then a chemical reaction called cycloaddition transfers a dye onto the antibody making the cancer cells glow when viewed through a microscope.
Philip Dawson, a member of Faculty of 1000 Biology and leading authority in chemistry and cell biology, reviewed a study and observed that the novel cycloaddition reaction is fast, very specific, and requires minimal manipulation of the cells.
![Nanoparticles And Lasers Exposure Could Lead To New Way To Drug Delivery Into Cancer Cells]( "Nanoparticles And Lasers Exposure Could Lead To New Way To Drug Delivery Into Cancer Cells")
University of California, Santa Barbara (UCSB) researchers have developed a new way to deliver drugs into cancer cells by exposing them briefly to nanoparticles and lasers.
He comments that, in combining antibody binding with the cycloaddition, "low signal-to-noise ratios are achieved".
He points out that the new labeling technique could be used to track the location and activity of anti-cancer drugs, the location of cancer-specific proteins within the cell, or to visualize cancer cells inside a living organism.
Dawson concludes that cycloaddition will allow scientists to observe live cancer cells in the body, leading to a better understanding of cancer's basic processes.
Source: ANI
ARU
Nanoparticles And Lasers Exposure Could Lead To New Way To Drug Delivery Into Cancer Cells
University of California, Santa Barbara (UCSB) researchers have developed a new way to deliver drugs into cancer cells by exposing them briefly to nanoparticles and lasers.
Advertisement
He comments that, in combining antibody binding with the cycloaddition, "low signal-to-noise ratios are achieved".
He points out that the new labeling technique could be used to track the location and activity of anti-cancer drugs, the location of cancer-specific proteins within the cell, or to visualize cancer cells inside a living organism.
Dawson concludes that cycloaddition will allow scientists to observe live cancer cells in the body, leading to a better understanding of cancer's basic processes.
Source: ANI
ARU
Swiss Scientists Find Novel Way to Block Growth of Human Colon Cancer Cells
A novel way to inhibit the growth of human colon cancer cells and preventing the disease from reaching advanced stages and the development of liver metastases has been discovered by Swiss scientists.
Advertisement
Advertisement
|
Advertisement
Recommended Readings
Latest Cancer News
More affected relatives, higher lung cancer risk; participants with affected mothers or siblings faced increased risk.
Colorectal cancer can be lowered by up to 7% by increasing dietary consumption of folate rich foods like spinach, broccoli or taking folate supplements.
The effects and mechanisms of microRNA-451a (miR-451a), which hinders the progression of gemcitabine-resistant biliary tract cancers, are under study.
The blood test pinpointed 13 proteins capable of distinguishing between early and late stages of pancreatic cancer.
A fatty acid present in dairy products, beef, and lamb called trans-vaccenic acid enhances immune cells' capacity to combat cancers.