About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Potential Biomarker Can Help Identify Cancer Chemotherapy Timing

by Sushma Rao on April 19, 2018 at 11:40 AM
Font : A-A+

Potential Biomarker Can Help Identify Cancer Chemotherapy Timing

A new biomarker that can visualize the activity of blood vessels to identify the tumor normalizing period for effective timing of anti-cancer drug treatment, has been found by team of researchers.

Angiogenesis, the formation of new blood vessels, is essential for tumour growth.

Advertisement


The team from Osaka University in Japan, in a paper reported in The American Journal of Pathology, described a vascular stabilization biomarker that can visualize blood vessel activity, thus optimising the timing of anticancer therapies including anti-angiogenics.

Combination therapy using angiogenesis inhibitors and anticancer drugs can improve drug delivery into tumour tissues and prolong progression-free survival.
Advertisement

"Vascular normalisation by angiogenesis inhibitors, such as vascular endothelial growth factor (VEGF) signaling inhibitors, is a promising method for improvement of chemotherapy.

"However, it is unclear how we can recognise the 'window of opportunity' for the tumour vascular normalising period for effective timing of anti-cancer drug treatment. Therefore, biomarkers delineating this window are essential," explained Nobuyuki Takakura, Professor at Research Institute for Microbial Diseases, Osaka University.

Angiogenesis therapy is clinically used to suppress tumour growth.

Adding an anti-angiogenic drug can boost an anticancer drug's effectiveness.

Basic research indicates that anti-angiogenic therapy allows the blood vessels to return to quiescence and "normalise" so that the anti-cancer drug can penetrate the tumour more effectively.



Source: IANS
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
Long-Term Glycemic Control - A Better Measure of COVID-19 Severity
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cancer and Homeopathy Chronic Lymphocytic Leukemia Hodgkins Lymphoma Non-Hodgkins Lymphoma Chemotherapy Chemotherapy Drugs Cancer Facts Cancer Tattoos A Body Art Peritoneal Cancer 

Recommended Reading
Chemotherapy Drugs
Chemotherapy drugs perform like 'magic bullets' to destroy cancer cells in the body....
Chemotherapy
'Chemo' means medicine or 'drug'; 'therapy' means 'treatment'. Chemotherapy refers to the use of .....
Fifteen Most Common Chemotherapy Side Effects and Ways to Manage Them
Chemotherapy side effects depend on the chemotherapy treatment as there are varied types of ......
Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia (CLL) is one of the most common types of adult leukemia and is consider...
Hodgkins Lymphoma
Hodgkins lymphoma or Hodgkins disease has the distinction of being the first cancer to be cured by c...
Non-Hodgkins Lymphoma
Non Hodgkins Lymphoma is a cancer that affects the lymph tissues. It is made up of a wide array of ....
Peritoneal Cancer
Peritoneal cancer is a rare cancer that develops in the peritoneum. Peritoneal cancers may be primar...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use