Which Test can Detect Breast Cancer Metastasis Accurately?

Women with breast cancer, especially invasive lobular carcinoma need to be tested for lymph node metastases. The spread of cancer can be better detected with axillary biopsies.

Scientists have examined the accuracy of two tests that can help detect the spread of cancer to lymph nodes in women with breast cancer.

For patients diagnosed with breast cancer, determining whether cancer cells have spread to the axillary lymph nodes of the armpit is important for guiding treatment decisions.

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‘Invasive lobular carcinoma can be better detected in women with axillary biopsies, which help identify the spread of cancer to lymph nodes.’

It has been debated whether axillary ultrasound imaging is equally sensitive for detecting axillary metastatic lymph nodes in different subtypes of breast cancer.

A new BJS (British Journal of Surgery) study indicates that axillary ultrasound imaging is inferior for detecting axillary node metastasis in patients with invasive lobular carcinoma compared with invasive ductal carcinoma.

Therefore, women with invasive lobular carcinoma may benefit from axillary biopsies regardless of the ultrasonographic appearance of the nodes.

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The study included women diagnosed with invasive lobular carcinoma (602 women) or invasive ductal carcinoma (4199 women) in the West of Scotland in 2012-2014.

"Accurate preoperative staging of the axilla is important to allow decisions regarding neoadjuvant therapy to be made; it is also an important factor in the planning of postmastectomy radiotherapy and consequently may affect reconstructive options," wrote the authors.

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Source-Eurekalert

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