A new discovery has been made with the help of large DNA
analysis of humans, which says that there are several genetic markers to spot
pancreatic cancer.
The scientists from Dana-Farber Cancer Institute said
that the markers were variations in the inherited DNA code at particular
locations along chromosomes, and many of them signaled the increased risk of
developing the highly lethal disease.
Pancreatic Cancer
Pancreatic cancer often involves its exocrine part. It grows aggressively, and often detected late. Treatment options include surgery, radiation and chemotherapy.
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They analyzed DNA from 7,683 patients with pancreatic cancer and 14,397 control patients without this cancer, all of European descent, from the US, Europe, Canada, and Australia.
Brian Wolpin, MD, MPH, first author of the report, said that
the results confirmed the presence of four risk associated SNPs that had been
identified in a previous, smaller genome-wide association study (GWAS).
![Pancreatic Cancer Treated With]( "Pancreatic Cancer Treated With")
A new use for an old drug that shrinks a particular type of pancreatic cancer tumor and stops it spreading has been found by Cancer Research UK scientists.
In addition, five new risk markers were discovered and a sixth that was of borderline statistical significance. The risks associated to each SNP or marker were largely independent and additive, so that they may have utility in future attempts to identify individuals in the general population at higher risk for pancreatic cancer.
The average lifetime risk of pancreatic cancer is 1.5%. Pancreatic cancer is a cancer that occurs in the cells lining the ducts or the islet cells of the pancreas, a digestive organ that sits in the upper abdomen surrounded by the stomach, small intestine, liver, spleen and gall bladder.
The study is published online by Nature Genetics
Source: Medindia
Pancreatic Cancer Treated With 'Old' Drug in a New Way
A new use for an old drug that shrinks a particular type of pancreatic cancer tumor and stops it spreading has been found by Cancer Research UK scientists.
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In addition, five new risk markers were discovered and a sixth that was of borderline statistical significance. The risks associated to each SNP or marker were largely independent and additive, so that they may have utility in future attempts to identify individuals in the general population at higher risk for pancreatic cancer.
The average lifetime risk of pancreatic cancer is 1.5%. Pancreatic cancer is a cancer that occurs in the cells lining the ducts or the islet cells of the pancreas, a digestive organ that sits in the upper abdomen surrounded by the stomach, small intestine, liver, spleen and gall bladder.
The study is published online by Nature Genetics
Source: Medindia
Use of Low-dose Aspirin may Reduce Pancreatic Cancer Risk
The use of low dose aspirin may actually help an individual reduce his risk of developing pancreatic cancer, a new study has found
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