A single shot of DNA vaccine may help lower blood pressure for up to six months, says a new study.
According to the study in rats by American Heart Association, it suggested that the vaccine may eventually provide a novel alternative to treat high blood pressure in people, who would not need to take a pill everyday.
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Dr. Hironori Nakagami, study co-author and professor at Osaka University in Japan, said that the potential of a vaccine for hypertension offers an innovative treatment that could be very effective for the control of non-compliance which is one of the major problems in the management of hypertensive patients.
Researchers have designed a DNA vaccine that targets angiotensin II, a hormone that raises blood pressure by causing blood vessels to constrict and this narrowing can increase one's blood pressure and force one's heart to work harder.
![Positive Early Results Shown in Clinical Trial for DNA Vaccine]( "Positive Early Results Shown in Clinical Trial for DNA Vaccine")
Robust vaccine-specific antibody responses in all vaccinated patients evaluated to date were shown in the early results of a trial to treat leukaemia with a WT1 DNA vaccine.
In the study, researchers immunized hypertensive rats three times at two-week intervals with needle-less injections. The vaccine not only lowered blood pressure for up to six months, but also reduced tissue damage to the heart and blood vessels associated with hypertension and there were no signs of damage to other organs such as the kidney or liver.
The DNA vaccine works similar to common ACE inhibitor blood pressure medications which help blood vessels relax and open up, which, in turn, lowers blood pressure.
The research is published in American Heart Association Rapid Access Journal Report.
Source: Medindia
Positive Early Results Shown in Clinical Trial for DNA Vaccine
Robust vaccine-specific antibody responses in all vaccinated patients evaluated to date were shown in the early results of a trial to treat leukaemia with a WT1 DNA vaccine.
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In the study, researchers immunized hypertensive rats three times at two-week intervals with needle-less injections. The vaccine not only lowered blood pressure for up to six months, but also reduced tissue damage to the heart and blood vessels associated with hypertension and there were no signs of damage to other organs such as the kidney or liver.
The DNA vaccine works similar to common ACE inhibitor blood pressure medications which help blood vessels relax and open up, which, in turn, lowers blood pressure.
The research is published in American Heart Association Rapid Access Journal Report.
Source: Medindia
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Latest Hypertension News
In the majority of cases, it is advisable to allow patients' blood pressure to self-regulate following endovascular treatment.
Blood pressure (BP) is a silent killer that is progressively impacting Indians, regardless of age, affecting both the young and the elderly.
Several AI-backed blood pressure-analyzing instruments are available to assist patients in monitoring their blood pressure and other crucial vital signs.
In India, there has been an increase in high blood pressure cases among youngsters, highlighting the necessity for effective measures to increase awareness.
High blood pressure is often referred to as the "silent killer" because it doesn't exhibit any noticeable symptoms like fever or infection.
