About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Near-Death Brain Signals May Be Targeted To Save Life In Case Of Sudden Cardiac Arrest

by Bidita Debnath on April 8, 2015 at 1:23 AM
Font : A-A+

Near-Death Brain Signals May Be Targeted To Save Life In Case Of Sudden Cardiac Arrest

In case of sudden cardiac arrest, despite the loss of consciousness and absence of signs of life, a storm of brain activity erupts as the heart deteriorates and plays a surprising destabilizing role in heart function, says research.

This near-death brain signaling may be targeted to help cardiac arrest patients survive, say the team from University of Michigan after analyzing lab tests on animals.

Advertisement

"Despite the absence of signs of life, internally the brain exhibits sustained, organized activity and increased communication with the heart, which one may guess is an effort to save the heart," said Dr. Jimo Borjigin, senior study author, associate professor of neurology.

However the brain signaling at near-death may, in fact, accelerate cardiac demise. To understand this, the researchers looked at the mechanism by which the heart of a healthy person ceases to function within just a few minutes without oxygen.
Advertisement

They simultaneously examined the heart and brain during experimental asphyxiation and documented an immediate release of more than a dozen neurochemicals, along with an activation of brain-heart connectivity. Following a steep fall of the heart rate, brain signals strongly synchronized with the heart rhythm, as visualized beat-by-beat using a new technology developed in the Borjigin laboratory called electrocardiomatrix.

According to the study, blocking the brain's outflow significantly delayed ventricular fibrillation, in which the lower chambers of the heart quiver and the heart cannot pump any blood. It is the most serious cardiac rhythm disturbance.

"The study suggests that a pharmacological blockade of the brain's electrical connections to the heart during cardiac arrest may improve the chances of survival in cardiac arrest patients," Borjigin said.

The findings provide a neurochemical foundation for the surge in brain activity and a brain-heart connectivity that may be targeted to lengthen detectable brain activity, said the study published in the journal PNAS.

Source: IANS
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Ways to Manage Stress during COVID-19 Pandemic
Can Adjusting Fatty Acid Intake Improve Mood in Bipolar Disorder Patients?
Insulin Resistance Doubles the Risk of Major Depressive Disorder
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Chest Pain Parkinsons Disease Parkinsons Disease Surgical Treatment Palpitations And Arrhythmias Cardiac Catheterization Brain Brain Facts Ataxia Statins Cardiomyopathy 

Recommended Reading
Survival and Brain Function in Comatose Cardiac Arrest Survivors may be Predicted by Heart Rate
A way to potentially assist prognostication in the first 24 hours after out-of-hospital cardiac ......
Daily High Pollution Levels 'Elevate' Cardiac Arrest Rates
Cardiac arrest rates are higher a few days after the increase in levels of several air pollutants, ....
Survival Increases With Structured Team Debriefing After In-Hospital Cardiac Arrest
Staff members who joined structured team debriefings after emergency care for children suffering ......
Ataxia
Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or ...
Cardiac Catheterization
Cardiac catheterization is a radiological procedure for both diagnosis and treatment of heart condit...
Cardiomyopathy
Cardiomyopathy weakens the heart muscles and the heart loses strength to pump blood throughout the b...
Chest Pain
Ask any one who has experienced intense chest pain and they will vouch for the fact that it was the ...
Palpitations And Arrhythmias
Palpitations are unpleasant sensation of one’s own heartbeat....
Parkinsons Disease
Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Statins
Statins are new wonder drugs that are proving to be efficacious, not merely in relieving symptoms bu...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use