The suppression of the differentiation of adipocytes with Mallotus furetianus is regulated through the post-translational modifications of C/EBPβ
Go to source). A multi-institutional research group led by Associate Professor Akiko Kojima of the Graduate School of Human Life and Ecology at Osaka Metropolitan University has made significant progress in the fight against obesity.
Malnutrition to Obesity - The Big Leap
Obesity is the root cause of problems like diabetes, heart disease, stroke, arthritis and gall bladder disease. A serious look at our strategies is needed to tackle this fast growing epidemic.
Obesity is the root cause of problems like diabetes, heart disease, stroke, arthritis and gall bladder disease. A serious look at our strategies is needed to tackle this fast growing epidemic.
‘Breakthrough discovery reveals that Mallotus furetianus, a tropical plant from Hainan Island, China, possesses anti-obesity effects, presenting a potential solution to the widespread issue of obesity and its associated lifestyle diseases.
# Obesity, #Tropical Plant, #China
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The group had previously conducted a study on the effects of the extract of Mallotus furetianus (MFE), a tropical plant native to Hainan Island, China, on the prevention of fatty liver, but the anti-obesity effects of MFE and its mechanisms had not been elucidated until now. The Solution for Obesity Epidemic
Using obesity model mice, the researchers set out to verify the anti-obesity effects of MFE extract and the results were remarkable.Treatment with MFE significantly suppressed the increase in body weight and adipose tissue weight and also demonstrated morphological changes in the liver and adipose tissue of the obesity model mice. Further investigation into the mechanism revealed that fat synthesis was inhibited by suppressing the expression of several transcription factors involved in adipocyte differentiation.
“Our research group is searching for food ingredients with anti-obesity effects, based on the idea that if we can find and incorporate them into our daily diets, we can contribute to people's health and longevity,” stated Professor Kojima.
Obesity
Obesity is a condition where there is excess accumulation of body fat which poses a risk to the health of the individual. It can affect children and adults.
Obesity is a condition where there is excess accumulation of body fat which poses a risk to the health of the individual. It can affect children and adults.
Reference:
- The suppression of the differentiation of adipocytes with Mallotus furetianus is regulated through the post-translational modifications of C/EBPβ - (https://onlinelibrary.wiley.com/doi/10.1002/fsn3.3551)
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