During the bash, the 33-year-old supermodel said: "Who's got the drugs? Get me some gear!"
The DJ at the party, Elliot Eastwick said that Moss was a total nightmare.
"She was a total nightmare. It was obvious she was on drugs. I've seen enough drugged-up people to know," the Mirror quoted Eastwick, as saying.
"Even though I'd met Kate before I didn't recognise her at first. She had her hair in pigtails and was wearing tight wet-look leggings, a top and a black leather jacket.
"She seemed leathered already - sweaty, fidgety, and desperate to dance," he added.
Elliot also revealed that Moss' head lolled back as she sunk into a high after snorting from a bottle of alkyl nitrate, known as "poppers".
"Kate pulled some poppers out of her handbag and started snorting them in really heavily. It went straight to her head. You could see her loll as it took effect," he said.
At the same party, Moss and Sienna Miller had a row over Miller's beau Rhys Ifans.