Changes in moral behavior, and not memory loss, causes loved ones of patients with neurodegenrative diseases to say that the patient was not 'the same person'.

The research team recruited 248 participants with family members suffering from one of three types of neurodegenerative disease- frontotemporal dementia, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS). Both frontotemporal dementia and Alzheimer's disease are associated with cognitive changes, and frontotemporal dementia is specifically associated with changes to frontal lobe function that can affect an individual's moral behavior. ALS is primarily associated with loss of voluntary motor control.
The study participants, mostly spouses or partners of the patients, reported the extent to which their loved one showed various symptoms typical of their disease (rating each symptom as none, mild, moderate, or severe). The findings revealed that both Alzheimer's disease and frontotemporal dementia were associated with a greater sense of identity disruption than ALS, with frontotemporal dementia leading to the greatest deterioration in identity. The research team determined that perceived identity change was strongly linked with change in moral traits.
These findings are published in Psychological Science.
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