About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Mass Vaccinations Do Not Prevent Ebola Virus Outbreaks

by Adeline Dorcas on May 10, 2018 at 1:09 PM
Font : A-A+

Mass Vaccinations Do Not Prevent Ebola Virus Outbreaks

Prophylactic mass vaccination programmes are unrealistic and not a practical alternative in combating Ebola virus outbreaks, reports a team of researchers from the University of Kent.

The findings come as the World Health Organisation has announced a new Ebola virus outbreak in the Democratic Republic of Kongo.

Advertisement


The team analyzed the prospects for various Ebola virus vaccines and found that, for the foreseeable future at least, Ebola virus outbreak control depends on surveillance and the isolation of cases.

The researchers' analysis revealed that very high proportions of potentially affected populations would need to be protected by vaccination to establish herd immunity, i.e., the level of immunity that prevents virus transmission within a population.
Advertisement

The study, entitled Herd immunity to Ebola viruses is not a realistic target for current vaccination strategies identified that, in the critical phases of many Ebola virus outbreaks, the average infected individual infects four or more other people, which enables the virus to spread rapidly.

At this level, 80% of a population would need to be immunized to prevent outbreaks, even if a highly effective vaccine that protects 90% of individuals after vaccination was available.

Such vaccination rates are currently unachievable. In a vaccination trial during the West African Ebola virus epidemic, only 49% of individuals who had been in contact with Ebola virus patients could be vaccinated. Thirty-four percent of contacts refused vaccination although they had been exposed to the disease.

There are currently no clinical vaccine candidates available that protect against all four human-pathogenic Ebola viruses. It also remains unclear, say the researchers led by Professor Martin Michaelis, of Kent's School of Biosciences, whether the available vaccine candidates provide the long-term protection (? 10 years) that is required for the sort of prophylactic mass vaccination programme that could prevent Ebola, which becomes repeatedly introduced into the human population from animal reservoirs.

A large vaccination programme would also be costly and impractical, the study points out. Costs for current Ebola virus vaccine candidates are estimated to be in a range of US$ 15-20 per dose, with some 462 million people living in the areas affected by Ebola virus outbreaks, many of them in very remote rural areas.

In the absence of a realistic prophylactic mass vaccination programme, the researchers conclude that clinical vaccine candidates will need to be focused on health care workers who are often involved in disease transmission, potentially in combination with the vaccination of patient contacts.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Turmeric: Magic Ingredient to Keep you Healthy in Winter
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Chicken Pox Shigellosis Bioterrorism Congo Fever Ebola Virus Disease Traveling with Children Abroad? - Parents, Stay Alert! 

Recommended Reading
Ebola Virus Disease
Ebola is caused by a virus via direct contact with body fluids or infected blood. Scientists have .....
Ebola-Related Deaths Fell When Treated With High Dose of Antiviral Drug
High doses of the antiviral drug called favipiravir maybe effective in preventing deaths form Ebola ...
New Formula for Ebola Vaccine Proves Effective
Ebola virus disease vaccine was developed to control the epidemic as the treatment for ebola is ......
New Ebola Virus Antibody Paves the Way for Future Vaccines and Therapy
Natural human antibodies isolated from the blood of an Ebola survivor has been shown to neutralize ....
Chicken Pox
Chicken pox is an acute and highly contagious viral infection caused by the varicella zoster virus....
Congo Fever
Crimean-Congo Hemorrhagic fever (CCHF) is a viral disease that affects people who are bitten by infe...
Shigellosis
Shigellosis or Bacillary Dysentery is a common cause of gastro-enteritis worldwide and can cause blo...
Traveling with Children Abroad? - Parents, Stay Alert!
Traveling with children is always challenging as it involves careful planning. Here are some precaut...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use