About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Identifying Kidney Damage Risk in Kids and Teens After First UTI

by Himabindu Venkatakrishnan on August 5, 2014 at 11:07 AM
Font : A-A+

 Identifying Kidney Damage Risk in Kids and Teens After First UTI

Bottom Line: High risk for renal scarring with first Urinary tract infection (UTI) in children and adolescents with abnormal kidney ultrasonography finding or with fever of at least 102 degrees and infected with organism other than E.Coli.

Author: Nader Shaikh, M.D., of the Children's Hospital of Pittsburgh, and colleagues.

Advertisement

Background: UTIs are a common and potentially serious bacterial infection in young children. UTIs can lead to permanent renal scarring in up to 15 percent of cases in this population. Significant scarring can lead to reduced kidney function, which has been associated with hypertension, pre-eclampsia and end-stage renal disease later in life.

How the Study Was Conducted: The authors reviewed available medical literature to identify factors linked to the development of renal scarring and to develop a clinical prediction model that could be used to identify children at risk for scarring. The meta-analysis included data from nine cohort studies with 1,280 children (up to age 18 years).
Advertisement

Results: Of the 1,280 children, 199 (15.5 percent) had renal scarring. Factors associated with renal scarring were a fever of at least 102 degrees, infection with an organism other than E.coli, an abnormal kidney ultrasonography finding, polymorphonuclear cell count of greater than 60 percent, C-reactive protein level of greater than 40 mg/L and the presence of vesicoureteral reflux (abnormal urine flow backward from the bladder to the urinary tract). Children appear to have twice the baseline risk of scarring if they have an abnormal kidney ultrasonography finding or with a combination of a fever of at least 102 degrees and infection with an organism other than E.coli. According to the authors, this prediction model could be used to identify nearly 45 percent of the children who go on to scar.

Discussion: "Early identification of children at risk for renal scarring using the prediction rules developed in this study could help clinicians deliver specific treatment and follow-up for this small subgroup in the future."

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Diet and Oral Health: The Sugary Connection May Become Sour
World AIDS Day 2022 - Equalize!
Test Your Knowledge on Sugar Intake and Oral Health
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Urinary Tract Infection Height and Weight-Kids Urinary Stones In Children Vesico-Ureteric Reflux Causing UTI in Children Hydronephrosis / Antenatal Counseling Kidney Disease Kidney Kidney Health Stones in Urinary Tract Renal Tubular Acidosis 

Most Popular on Medindia

A-Z Drug Brands in India How to Reduce School Bag Weight - Simple Tips Calculate Ideal Weight for Infants Drug Interaction Checker Find a Hospital Post-Nasal Drip Nutam (400mg) (Piracetam) Blood Pressure Calculator Drug Side Effects Calculator Noscaphene (Noscapine)
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Identifying Kidney Damage Risk in Kids and Teens After First UTI Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests