New study determined whether the use of edible cannabis during pregnancy is deleterious to the fetal growth and the genes regulating placental development.
- Many women wonder if consuming cannabis in edible form is safe during pregnancy
- A new study has found a link between cannabis use during pregnancy and possible behavioral impairments in growing fetus //
- Hence, using cannabis might be legally acceptable but that does not mean it’s safe for your unborn child





Cannabis Exposure During Critical Windows of Development: Epigenetic and Molecular Pathways Implicated in Neuropsychiatric Disease
Go to source). Keeping this in mind, a new study aimed to identify the potential long-term health impacts of THC use during pregnancy.
Cannabis Use During Pregnancy and Its Relationship with Fetal Developmental
Researchers conducted the study in a model using nonhuman primates. They administered THC in a daily edible and compared its effects to a group receiving a placebo. Specifically, researchers evaluated the epigenetic changes in areas that indicate healthy prenatal development such as the placenta, fetal lung, brain, and heart.When looking at these areas, researchers found that THC exposure during pregnancy altered the placental and fetal epigenome —including the chemical modifications to DNA responsible for gene regulation and expression (2✔ ✔Trusted Source
Prenatal delta-9-tetrahydrocannabinol exposure is associated with changes in rhesus macaque DNA methylation enriched for autism genes
Go to source).
Genes are the segments which make up DNA — are all specifically coded to contribute to different functions of the body and brain, so any impact due to drug exposure is concerning, especially during a critical developmental window such as pregnancy.
They also found that that these changes to gene regulation and expression are consistent with those seen with many common neurobehavioral conditions, including autism spectrum disorder. These conditions are linked to adverse health outcomes including poor memory and verbal reasoning skills, and increased hyperactivity, impulsivity, and inattention.
These study findings will add to the limited existing knowledge on THC use during pregnancy, and help guide patient counselling and drafting public health policies focused on cannabis in the future. Cannabis is one of the most used drugs, so there is a common perception that it’s completely safe to use. But the reality is that cannabis still carries many health risks for certain populations, including those who are pregnant (3✔ ✔Trusted Source
The Placental Epigenome as a Molecular Link Between Prenatal Exposures and Fetal Health Outcomes Through the DOHaD Hypothesis
Go to source).
References:
- Cannabis Exposure During Critical Windows of Development: Epigenetic and Molecular Pathways Implicated in Neuropsychiatric Disease(https://link.springer.com/article/10.1007/s40572-020-00275-4)
- Prenatal delta-9-tetrahydrocannabinol exposure is associated with changes in rhesus macaque DNA methylation enriched for autism genes(https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-023-01519-4)
- The Placental Epigenome as a Molecular Link Between Prenatal Exposures and Fetal Health Outcomes Through the DOHaD Hypothesis(https://link.springer.com/article/10.1007/s40572-022-00354-8)