- Raspberries are rich in antioxidants,
vitamins and dietary fiber
- Red raspberries play an important
role in post meal glycemic control in individuals with hyperinsulinemia
- They increase satiety, reduce
inflammation and improve gut health
offer an array of health benefits from improving glucose control, increasing
satiety and reducing inflammation. Initial findings of several studies on the
health benefits of red raspberries were presented at the 2017
Experimental Biology conference in Chicago.
included both human subjects and animals. Short-term trials conducted on humans
showed that consumption of raspberries improved glucose control and satiety.
Long-term animal trials showed positive effect on the gut microbiota. The
results of the studies provide insights for future research on the potential
benefits of red raspberries related to reducing the
risk of inflammation, obesity and type 2 diabetes.
‘Polyphenolic phytochemicals, fiber, and essential nutrients found in red raspberries play a role in reducing inflammation, improving blood sugar control and increasing satiety.’
excited about this new flurry of studies, which builds on previously published
research aimed to understand the potential health benefits of red raspberries
better. Our Council is committed to delivering the highest quality nutrition
and health science that consumers can use to make informed choices when aiming
for a healthy diet," said Tom Krugman, Executive Director of the National
Processed Raspberry Council (NPRC).
studies on humans are warranted, the initial findings of these studies suggest
that vital nutrients, polyphenolic phytochemicals and fiber found in
raspberries may play a key role in supporting metabolic functions, including
anti-oxidative, anti-inflammatory and metabolic stabilizing activity.
are rich in dietary fiber and polyphenols that can improve the health of
individuals at risk for developing diabetes mellitus
. A research
team at the Center for Nutrition Research, Institution for Food Safety and
Health, Illinois Institute of Technology, Chicago conducted the effect of red
raspberries on meal-induced postprandial metabolic responses. The study
comprised of obese individuals with impaired fasting glucose and
hyperinsulinemia (PreDM) and healthy weight individuals with normo-glycemia and
The findings of
the study published in the FASEB Journal
suggest that red
raspberries improved insulin sensitivity in individuals with pre-diabetes and
Red raspberries have a role in post meal glycemic
control in individuals with hyperinsulinemia.
The study also
had a secondary objective in assessing the effects of red raspberries in
improving satiety. The research team found that the participants in the PreDM
group who reported the highest level of hunger experienced greater satiety
after the consumption of red raspberries. The participants in the healthy
weight group were also given 2 cups of raspberries for breakfast. The
participants experienced significantly greater hunger suppression, after a raspberry meal compared to the same calorie breakfast
A research team
from the Institute for Food Safety and Health from the Illinois Institute of
Technology conducted an eight-week pilot study to examine the impact of
consumption of red raspberry purée on the gut microbiota. Consumption of red
raspberry puree for four weeks resulted in decreased Firmicutes and increased
The team found
that a type of bacteria called Akkermansia, which is associated with
metabolic health, increased only after the consumption of red raspberry purée.
The preliminary results of the study are promising.
However, further research is needed to show that consumption of raspberry purée
may change the composition of the gut microbiota.
was conducted to find out if red raspberries can
modulate the fecal microbiota in obese mice with diabetes and dyslipidemia
. Dr. Giuliana Noratto and colleagues of the Department of Food and Nutrition
Science at Texas A&M University found that red raspberry supplementation
increased the number of Lachnospiraceae. Lachnospiraceae is a family of
bacteria that can be depleted during diseases of the intestinal tract such as inflammatory
Crohn's disease and ulcerative colitis. The findings of
the study provide a base for additional studies involving human participants.
Insulin Sensitivity with Cardio-protective
contain polyphenolics that promote adipose tissue browning and increase lipid
oxidation. But the role of polyphenolics in skeletal muscle intracellular lipid
accumulation and inulin resistance is unclear. A study conducted on mice found
that supplementation of 5% dried raspberry for 12 weeks improved insulin
resistance and reduced inflammation in skeletal muscle while consuming a
The findings of the study give support to a short-term study
in humans conducted by Xiao and colleagues.
A research team
from the University of Michigan studied the antioxidant and anti-inflammatory
properties of red raspberries. A study was conducted to mice to explore the
potential relationship between feeding freeze-dried whole raspberry powder and
the risk of cardiometabolic risk in obese rats. They found that red raspberries
upregulated the expression of specific cardiac-protective molecular proteins -
myocardial adiponectin, its receptor 2, and apolipoprotein E.
Mice fed with
red raspberries experienced altered nicotinamide phosphoribosyltransferase
mRNA, a protein associated with obesity
and type 2
. The team said that
more research is needed to determine if compounds in red raspberries play a
role in human cardiometabolic pathways.
colitis causes mucosal injuries of the intestinal epithelium, increasing the
risk of colorectal cancer. Red raspberries are rich sources of phytochemicals that have beneficial
effects on colitis by reducing inflammation
conducted on mice found that supplementation of 5% dried red raspberry
suppressed inflammation, decreased body weight, improved the disease activity
index, and colon epithelium repair and wound healing.
Further studies are
needed to determine if supplementation of red raspberry supports epithelial
function in humans.
The results of
the studies are promising and contribute to the
understanding of the health benefits of red raspberries. The studies were
presented at the 2017 Experimental Biology conference in Chicago. Reference:
- Xiao, D. Huang, Y. Park, E. Edirisinghe, I. and Burton-Freeman, B. Red Raspberries and Insulin Action: Understanding the Role of Red Raspberry Consumption on Postprandial Metabolic Indices. The FASEB Journal, April 2017, vol. 31 no. 1 Supplement 973.9.
- Zhang, X. Sandhu, A. Schill, K. Edirisinghe, I. and Burton-Freeman, B. The Reciprocal Interactions between Red Raspberry Polyphenols and Gut Microbiome Composition: Preliminary Findings. The FASEB Journal, April 2017, vol. 31 no. 1 Supplement 965.29.
- Noratto, G. Garcia-Mazcorro, J. Chew, B. and Mertens-Talcott, S. Dietary Supplementation with Raspberry Whole Fruit Modifies the Relative Abundance of Fecal Microbial Communities in Obese Diabetic (db/db) Mice. The FASEB Journal, April 2017, vol. 31 no. 1 Supplement 965.19.
- Min Du, Tiande Zou, Bo Wang, Xingwei Liang, and Mei-Jun Zhu. Raspberry intake reduces skeletal muscle lipid accumulation and improves insulin sensitivity in mice fed high fat diet. The FASEB Journal, April 2017, vol. 31 no. 1 Supplement 972.19.
- Kirakosyan, A. Seymour, EM. Gutierrez, E. and Bolling, S. Associations of Dietary Intakes of Red Raspberry Fruits with Risk of Type 2 Diabetes Mellitus. The FASEB Journal, April 2017, vol. 31 no. 1 Supplement 973.4.
- Bibi, S. Du, M. Kang, Y. Sun, X. Xue, Y. Soussa Moraes, LF. and Zhu, M. Dietary Red Raspberry Enhances Intestinal Epithelium Repair in Chronic Colitis. The FASEB Journal, April 2017, vol. 31 no. 1 Supplement 972.19.