One in every four drugs can affect good gut bacteria with their side effects, finds a new study. These drugs can also cause antibiotic-like side-effects on the gut bacteria.
Gut Bacteria Drive Autoimmune Diseases
Targeting gut bacteria with an antibiotic or vaccination may offer a promising new treatment approach for autoimmune diseases.
Targeting gut bacteria with an antibiotic or vaccination may offer a promising new treatment approach for autoimmune diseases.
‘A surprisingly huge number of unrelated drugs can affect the gut bacteria negatively. They can even change the gut microbiome composition. This change in the composition of gut bacteria can contribute to bad digestive health.’
Widespread phenomenon The human gut contains a large number of species of bacteria, collectively referred to as the gut microbiome. In the last decade, it has become clear that the composition of the gut microbiome affects human health. It is well-known that antibiotics have a large impact on this microbiome, for example causing gastrointestinal side effects.
Recently, a few commonly used non-antibiotic drugs have been shown to cause changes in gut microbiome composition, but the full extent of this phenomenon was unknown until now. The current paper is the first to systematically profile direct interactions between marketed drugs and individual gut bacteria. Not only anti-infectives but drugs from all therapeutic classes inhibited the growth of different gut microbes.
Stress Caused Due to Social Conflicts can Alter Gut Bacteria
Conflicts can do more than just upset our moods, it can also alter our gut bacteria and that too in a bad way, finds a new study.
Conflicts can do more than just upset our moods, it can also alter our gut bacteria and that too in a bad way, finds a new study.
Kiran Patil adds: "This is just the beginning. We don't know yet how most of these drugs target microbes, how these effects manifest in the human host, and what the clinical outcomes are. We need to carefully study these relationships, as this knowledge could dramatically improve our understanding and the efficacy of existing drugs."
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Gut Bacteria can Alter Diet Necessary to Reduce Blood Pressure
Natural gut bacteria can alter the effectiveness of a diet change, considered to be effective in reducing high blood pressure finds a new study.
Natural gut bacteria can alter the effectiveness of a diet change, considered to be effective in reducing high blood pressure finds a new study.
The study also highlights the previously unnoticed risk that consumption of non-antibiotic drugs may promote antimicrobial resistance, as the general resistance mechanisms of microbes to human-targeted drugs and to antibiotics seem to largely overlap.
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C-sections and Gut Bacteria May Up Childhood Obesity Risk
An overweight or obese woman when delivering vaginally, the risk of overweight in her child is three times higher, and when giving birth via cesarean-section (C-section), the risk is five times higher than usual.
An overweight or obese woman when delivering vaginally, the risk of overweight in her child is three times higher, and when giving birth via cesarean-section (C-section), the risk is five times higher than usual.
Personalised medicine
"We are excited to move on and explore drug-microbe interactions in complex gut microbial communities, as this will help us understand how individuals sometimes respond differently to the same medication," says Georg Zeller. Each of us harbors a unique gut microbiome. We all carry different bacterial species - besides several common ones - and on top of that, we carry different individuals of the same species called strains. These strains can have very different functionalities, including the response to drugs. Therefore, many drug-microbe interactions are likely to be individual, opening paths for personalized drug therapies aimed at the individual gut microbiome.
Source-Eurekalert
