Epilepsy Deaths Didn't Reduce Despite Advances In Therapy

New research found that mortality rates for epilepsy-related deaths did not decrease between 2009 (6.8 per 100,000) and 2015 (9.1 per 100,000), despite advances in treatment during this time.

Epilepsy-related deaths in young adults aged 16-24 years remain large, according to the new study presented at the European Academy of Neurology (EAN) Virtual Congress.

The research found that mortality rates for epilepsy-related deaths did not decrease between 2009 (6.8 per 100,000) and 2015 (9.1 per 100,000), despite advances in treatment during this time.

‘Most common causes of death due to epilepsy were sudden unexpected death, aspiration pneumonia, cardiac arrest, congenital malformation and alcohol-related deaths.’
Read More..

Young adult patients in their early 20s and 30s were found to be at the highest risk, with 78% of epilepsy-related deaths under the age of 55 years classified as potentially avoidable.

The study is being conducted in Scotland and looks to identify the burden of epilepsy-related deaths, what proportion of these are potentially avoidable, and ascertain the factors that may put patients at an increased risk.

The researchers collected anonymous data from healthcare settings for patients that died between 2009 and 2016, identifying 2,149 epilepsy-related deaths. 60% of these patients (1,276) had one or more seizure-related or epilepsy-related hospital admission in the years prior to death, yet less than a quarter (516) were seen in a neurology clinic.

The most common causes of death within the study were sudden unexpected death in epilepsy (SUDEP), aspiration pneumonia, cardiac arrest, congenital malformation and alcohol-related deaths.

The data will be compared with data from living patients with epilepsy of the same age and gender. These comparisons will focus on the patients’ epilepsy type, socio-economic class, standards of care received, and the presence of additional disorders, such as depression.

Dr Gashirai Mbizvo, completing this Scottish Epilepsy Deaths Study (SEDS) at The University of Edinburgh, comments that "Epilepsy patients are at a higher risk of early death than the general population, but reasons for this are unclear.

We hope that we can use this data to learn lessons and reduce the burden of epilepsy-related deaths in the future, many of which we believe are likely to be avoidable. Highlighting such risk factors, and identifying those that could be prevented, might lead to changes in epilepsy care and, ultimately, fewer epilepsy-related deaths in the future."

Epilepsy In Children | Seizures In Children - Causes, Complications, Types, Diagnosis, Treatment and Prevention
Epilepsy or seizures are caused by abnormal electrical activity in the brain and seen fairly commonly in children. Symptoms can be highly variable and parents should seek prompt medical advice to treat the condition

Epilepsy is a chronic noncommunicable disease of the brain that affects around 50 million people globally, making it one of the most common neurological diseases worldwide. It can cause seizures or periods of confusion in patients, which can either occur randomly or from triggers, such as a lack of sleep, stress or drinking alcohol. In many cases, people with epilepsy suffer from negative stigma and discrimination.

Source-Eurekalert