About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Eating Fat-rich Diet During Puberty Can Cause Breast Cancer

by VR Sreeraman on September 1, 2010 at 5:26 PM
Font : A-A+

 Eating Fat-rich Diet During Puberty Can Cause Breast Cancer

Eating a high-fat diet during puberty is associated with a greater risk of breast cancer later in life, according to a preliminary research.

The findings come from research at Michigan State University's Breast Cancer and the Environment Research Center.

Advertisement

Physiology professor Sandra Haslam, director of the center, and Richard Schwartz, microbiology professor and associate dean in the College of Natural Science, are now expanding that research.

"The pubertal time period is crucial, as this is when the basic framework is created for mammary gland development. What we are seeing from preliminary research in animals is that a high-fat diet during puberty can lead to the production of inflammatory products in the mammary glands of adults, which can promote cancer growth," Haslam said.
Advertisement

The work is based on the team's previous research that found the hormone progesterone activates genes that trigger inflammation in the mammary gland; that inflammation may be a key factor in increasing the risk of breast cancer.

The researchers discovered that a high-fat diet during puberty produced many of the same effects seen as part of their progesterone research.

Schwartz said: "Understanding what genes were turned on by progesterone led us to look at some of the same suspects with high-fat diets. It appears both processes may lead to inflammation in the mammary glands."

Since these inflammatory changes first occur during the crucial time of puberty, a period of intense development and cell division, it can have effects lasting a lifetime.

To test their findings, Haslam and Schwartz will lead a team analyzing two different mouse models of breast cancer and the effects of high-fat diets during puberty. They also will test several anti-inflammation interventions designed to overcome the negative effects of a high-fat diet on inflammation.

Source: ANI
Advertisement

Advertisement
Advertisement

Recommended Reading

Latest Cancer News

Combination Therapy may Benefit Leukemia Patients
The new study uncovers the efficacy of fixed-duration combination treatment in patients with high-risk leukemia.
 Myelofibrosis: New Drugs to Revolutionize Treatment
The approvals of pipeline drugs such as momelotinib and Vonjo for myelofibrosis (a rare type of blood cancer) over some time will handle the critical unmet needs.
 Blood Vessels Can Kill Cancer Cells and Stop Breast Cancer Spread
New study highlights the dual role that blood vessels can play in cancer immunotherapy and eliciting anti-tumor immune responses or even preventing breast cancer spread.
 Weed Killer Agent Orange May Increase the Risk of Blood Cancer Among Veterans
New study evaluated the association between exposure to the chemical agent orange and the development of blood cancer with increased bleeding and blood clot formation.
Two Years: Optimal Duration of Immunotherapy in Advanced Lung Cancer
Study suggests two-year immunotherapy treatment for advanced lung cancer may be reasonable
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Eating Fat-rich Diet During Puberty Can Cause Breast Cancer Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests