Multiple sclerosis (MS) patients who followed their medication schedules were found to have better physical outcomes and also the overall costs for care were higher, reveals a new study.
Researchers examined the insurance claims and medical records of 681 patients with MS.
Multiple Sclerosis
Multiple sclerosis can be a severely disabling autoimmune disease that affects the myelin or insulating layer of the nerve fibers and typically has remissions and relapses
Advertisement
‘Multiple sclerosis (MS) patients who adhere to medication have increased cost, but their physical outcomes are much better.’
Tweet it Now
The findings, published in the Journal of the American Osteopathic Association, are considered significant because it is harder to assess treatment results for patients with MS than for those with other chronic illnesses, making it difficult to determine whether the treatment benefits justify their cost.
Researchers noted that the disease has few easily obtainable objective measures, like blood pressure or glucose levels.
For patients with MS, disease activity is primarily measured through imaging studies, which can identify new lesions in the event of a relapse. Those studies are expensive and aren't routinely performed or captured in a quantitative fashion.
![Multiple Sclerosis Treatment and Modify]( "Multiple Sclerosis Treatment and Modify")
Multiple sclerosis is treated with drugs that modify the course of the disease, suppress immunity and relieve symptoms.
"Payers often look at near-term improvement to determine whether a treatment is effective and worth the cost," says Carl Hoegerl, DO, a neurologist at the Liberty University College of Osteopathic Medicine and a co-researcher on this study.
"But the case for MS treatment becomes evident when you see that the rate of decline becomes much slower and less severe."
Comparing the experiences of MS patients with high adherence to treatments to those with low adherence, the study found patients with highest adherence reported the disease's physical impact as 14 percent less severe and the psychological impact 17 percent less severe.
Patients with high adherence also rated their level of disability 12 percent lower and believed their treatments to be 7 percent more effective.
Dr. Hoegerl said that patients with untreated MS face a sharper decline in their ability to walk and move. They can also experience pain, numbness and tingling in their extremities.
MS is the most common cause of neurologic disability in adults, with about 135 cases per 100,000 Americans. About 12,000 new cases of MS are reported annually. While there is no cure, 12 FDA-approved treatments are currently available for patients with the disease.
"As an osteopathic physician, I'm focused on partnering with patients to achieve their health goals, which for most MS patients involves maintaining their physical functions for as long as possible," said Dr. Hoegerl. "We know that proper treatment of MS improves the quality of patients' lives and extends them to almost the length of the average person."
The study was conducted at Geisinger Health System, an integrated delivery system in central and northeastern Pennsylvania that includes an insurance provider, Geisinger Health Plan.
The study included adults whose records included MS diagnostic codes and medication orders for MS therapies.
The two phase study of patients from January 1, 2004 to December 31, 2013 included a retrospective analysis of electronic health records and insurance claims plus a prospective analysis of self-reported medication adherence.
The health outcomes considered included inpatients admission, emergency room visits, outpatient appointments and health care costs. All-cause versus MS-related costs were calculated separately, with all costs adjusted for inflation to 2013 dollars.
Source: Eurekalert
For patients with MS, disease activity is primarily measured through imaging studies, which can identify new lesions in the event of a relapse. Those studies are expensive and aren't routinely performed or captured in a quantitative fashion.
Multiple Sclerosis Treatment and Modify
Multiple sclerosis is treated with drugs that modify the course of the disease, suppress immunity and relieve symptoms.
Advertisement
"Payers often look at near-term improvement to determine whether a treatment is effective and worth the cost," says Carl Hoegerl, DO, a neurologist at the Liberty University College of Osteopathic Medicine and a co-researcher on this study.
"But the case for MS treatment becomes evident when you see that the rate of decline becomes much slower and less severe."
Comparing the experiences of MS patients with high adherence to treatments to those with low adherence, the study found patients with highest adherence reported the disease's physical impact as 14 percent less severe and the psychological impact 17 percent less severe.
Patients with high adherence also rated their level of disability 12 percent lower and believed their treatments to be 7 percent more effective.
Dr. Hoegerl said that patients with untreated MS face a sharper decline in their ability to walk and move. They can also experience pain, numbness and tingling in their extremities.
MS is the most common cause of neurologic disability in adults, with about 135 cases per 100,000 Americans. About 12,000 new cases of MS are reported annually. While there is no cure, 12 FDA-approved treatments are currently available for patients with the disease.
"As an osteopathic physician, I'm focused on partnering with patients to achieve their health goals, which for most MS patients involves maintaining their physical functions for as long as possible," said Dr. Hoegerl. "We know that proper treatment of MS improves the quality of patients' lives and extends them to almost the length of the average person."
The study was conducted at Geisinger Health System, an integrated delivery system in central and northeastern Pennsylvania that includes an insurance provider, Geisinger Health Plan.
The study included adults whose records included MS diagnostic codes and medication orders for MS therapies.
The two phase study of patients from January 1, 2004 to December 31, 2013 included a retrospective analysis of electronic health records and insurance claims plus a prospective analysis of self-reported medication adherence.
The health outcomes considered included inpatients admission, emergency room visits, outpatient appointments and health care costs. All-cause versus MS-related costs were calculated separately, with all costs adjusted for inflation to 2013 dollars.
Source: Eurekalert
Chemotherapy
''Chemo'' means medicine or ''drug'', ''therapy'' means ''treatment''. Chemotherapy refers to the use of cytotoxic drugs in the treatment of cancer.
Advertisement
 Health Risks of Eating PorkPork is one of the most popular and widely consumed of all red meats, but how healthy is it? Find out whether you can eat pork in any form. | Advertisement
|
Advertisement
Recommended Readings
Latest Research News
The discovery deepens our understanding of m6A biology and stress granule formation, with implications for neurodegenerative diseases.
Trouble with sleep and the body's clock may increase your risk for Parkinson's, as per a new study.
New study uncovers a link between nocturnal hot flashes and Alzheimer's risk in menopausal women, suggesting a potential biomarker.
Our discovery revealed that a minority of individuals attributed their chronic pain to their brain's involvement.
Relative Energy Deficiency in Sport syndrome is overlooked by athletes and can be worsened by 'sports culture' due to its perceived short-term performance benefits.
