
Coming soon, men can take their own birth control pill with no side effects, suggests study.
Working on mice, the team found that a compound called JQ1 acts as an inhibitor to sperm production and also sperm mobility.
"Both of these are needed for fertility, but JQ1 prevents both," said Qinglei Li, an assistant professor in Texas A and M's College of Veterinary Medicine and Biomedical Sciences, who is a part of the team.
Martin Matzuk at Baylor College of Medicine and James Bradner at Dana-Farber Cancer Institute led the researchers.
Though the mice were given injections, the team believes that a pill could eventually be developed for the same results.
A male contraceptive pill has been talked about for decades, but so far none has been successfully created despite a strong demand.
While many men might be reluctant to take out the trash or ask for directions if they are lost, recent studies have shown that about 70 percent of men would be willing to take a birth control pill if it were available.
One drawback to many female contraceptives is that they sometimes interfere with hormones, especially estrogen. But Li said the team is confident that JQ1 does not affect testosterone levels in men, and appears to have no other side effects as well.
As with many discoveries, the JQ1 compound appears to have come about by accident.
It was originally used for anti-cancer treatments, but researchers found it was also an excellent compound in controlling fertility.
"This is an exciting step in male contraception. A compound with more specificity will be needed before clinical trials can be done for humans. It does not mean a male birth control just yet, but it is a great step forward in that direction," Li added.
Their work has been published in the journal Cell.
Source: ANI