Backstabbing Bacteria Ditch Colleagues and Actually Lessen Infection

Backstabbing bacterial cells that act in their own interests and do not cooperate with their infection-causing colleagues can actually reduce the severity of infection.

The selfish behaviour of these uncooperative bacteria could be exploited to treat antibiotic-resistant infections, according to research being presented at the Society for General Microbiology's autumn meeting today.

New and Improved Sunscreens Through Ancient Bacteria
A new study says that cyanobacteria - organisms that thrived on Earth before there was enough oxygen to block harmful ultraviolet light-could pave way for new and improved sunscreens.

Bacteria work together by using a well-studied communication system called Quorum Sensing (QS).

During infection, bacteria talk to each other using QS to coordinate the release of toxins.

Researchers at the University of Nottingham have discovered that in Staphylococcus aureus infections, bacteria defective in QS can benefit from 'opting out' of toxin production.

Charitable Behavior Not Uncommon - Even in Bacteria
In a surprising discovery researchers at Boston University and the Wyss Institute for Biologically Inspired Engineering at Harvard have found that charitable behaviour

By doing so, they can invest more energy in reproducing - whilst taking advantage of the nutrient-rich infection that is maintained by their neighbours.

By looking after themselves in this way, QS-deficient bacteria are quickly able to outnumber other bacteria that are busy producing toxins.

Bacteria Resists Medical Treatment
Bacteria that had become drug-resistant pose a danger especially to healthcare institutions.

As a result the overall severity of infection is reduced as fewer toxins are produced.

"This opens up the interesting possibility of using these uncooperative bacteria to treat infection," said Eric Pollitt who is presenting the study.

Antibacterial Peptide Helps in Treatment of Soldiers' Burn Wound Infections
An antibacterial peptide promises to be effective in the treatment of infections caused by burn or blast wounds to soldiers.

The group tested the theory by introducing S. aureus into waxworms that subsequently developed infections.

"We found that the QS-deficient bacteria could not only outgrow normal bacteria in the same population, but that they could also invade other cooperating populations to reduce the severity of infection," explained Pollitt.

"This means that we could potentially isolate QS-deficient bacteria and use them to treat clinical S. aureus infections," he added.

Source-ANI