An automatic delivery system of propofol and remifentanil has been developed by an inventive team of French anesthesiologists.

Researchers have developed a proportional-integral-derivative controller which enables closed-loop administration of propofol and remifentanil, directed by the Bispectral Index (BIS) monitor, during administration of general anesthesia.
The delivery system has been tested on 196 surgical patients.
Source-Medindia