Antipsychotics Use in Alzheimer's Disease Persons can Reduce with Opioids

by Preethi Sivaswaamy Mohana on  March 27, 2018 at 12:38 PM Drug News
RSS Email Print This Page Comment bookmark
Font : A-A+

The use of antipsychotics and benzodiazepines in persons with Alzheimer's disease can be reduced by initiating opioid analgesics, according to a recent study from the University of Eastern Finland. The behavioral and psychiatric symptoms of dementia can be frequently treated with these opioids, which can be worsened by other symptoms, such as pain. The findings of the study are published in the journal International Psychogeriatrics.
Antipsychotics Use in Alzheimer's Disease Persons can Reduce with Opioids
Antipsychotics Use in Alzheimer's Disease Persons can Reduce with Opioids

The scientists analysed the use of antipsychotics and benzodiazepines six months before and six months after persons with Alzheimer's disease begun using an opioid. These results were then compared to persons with Alzheimer's disease who did not initiate opioid use. After the initiation of an opioid, the scientists found a downward trend in the prevalence of both antipsychotics and benzodiazepines, with the prevalence of antipsychotics reducing more.

The use of antipsychotics and benzodiazepines is very frequent in persons with Alzheimer's disease, but it carries a risk for severe adverse effects, and long-term treatment is generally not recommended. Previous studies have found a decrease in behavioural and psychiatric symptoms of dementia when patients are treated for pain, but this new study now shows, for the first time, a decrease in symptomatic drug use. The study is also the world's first nationwide study on the subject. The results provide further evidence on the importance of proper diagnosis and treatment of pain among persons with dementia.

The study is part of the MEDALZ cohort, which included 3,327 persons with Alzheimer's disease diagnosed during 2010-2011. Each person initiating opioid use was matched with a comparison person with Alzheimer's disease who did not initiate opioid use but was of the same age, gender and region of residence. Data for the study were derived from Finnish nationwide registers.



Source: Eurekalert
Advertisement

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Cannabis Drug Abuse Painkiller Addiction Prescription Drug Abuse 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive

Loading...