Antibiotic Prescription for Cough may Not Affect the Chance of Repeated Hospitalization

Children’s return to the hospitalization will not be affected by the antibiotic prescription which doctors or nurses prescribe very freely for cough.

Antibiotics prescribed by doctors and nurses don’t really reduce the risk of repeat hospitalization kids, finds a new study. The findings of this study are published in the British Journal of General Practice.

Antibiotics reduce the risk of children with a cough ending up in hospital, suggesting that this is an area in which unnecessary antibiotic prescribing could be reduced.

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‘Unnecessary prescription of the antibiotic need to reduced as it is a major contributor to the growing public health threat of antimicrobial resistance.’

The team, funded by the National Institute for Health Research, analysed data from a study of 8,320 children (aged three months to 15 years) who had presented to their GP with a cough and other respiratory infection symptoms to see whether adverse outcomes occurred within 30 days of seeing their GP.

Sixty-five (0.8 percent) children were hospitalised, and 350 (four percent) revisited their GP due to a worsening of symptoms.

Compared with no antibiotics, there was no clear evidence that antibiotics reduced hospitalization for children, supporting similar research findings in adults. However, there was evidence that a strategy of delayed antibiotic prescribing (giving parents or carers a prescription and advising they wait to see if symptoms worsened before using it) reduced the number of return visits to the GP.

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Immediate antibiotics were prescribed to 2,313 (28 per cent) and delayed antibiotics to 771 (nine per cent).

Dr. Niamh Redmond, from the Centre for Academic Primary Care at the University of Bristol and NIHR CLAHRC West, and lead author of the study said: "The good news is that most children who present to their GP with acute cough and respiratory infection symptoms are at low risk of hospitalization. We know that GPs, for a variety of reasons, commonly prescribe antibiotics in these cases as a precautionary measure. However, our study shows that antibiotics are unlikely to reduce this already small risk. This means that along with other strategies, there is real potential to reduce unnecessary antibiotic prescribing, which is a major contributor to the growing public health threat of antimicrobial resistance.

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"If a GP or nurse is considering antibiotic prescribing for a child presenting with acute cough, a delayed prescription may be preferable as we have shown that delayed prescribing reduces the need for further consultations."

Source-Eurekalert

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