Anti-cocaine Vaccine to Undergo Human Trials

During the study, researchers used PET, and discovered that the vaccine stopped cocaine from reaching the brain. The vaccine also activated the immune system to produce specific antibodies which latched on to cocaine molecules in the bloodstream. This stopped the drug from going through the blood-brain barrier.

"This is a direct demonstration in a large animal, using nuclear medicine technology, that we can reduce the amount of cocaine that reaches the brain sufficiently so that it is below the threshold by which you get the high," Crystal explained. Testing of this vaccine on humans is the next significant step before it becomes available for use.



Source: Medindia