Tuberculosis caused by Mycobacterium tuberculosis bacteria is an infectious disease that usually affects the lungs. The bacteria could alter their metabolism to combat exposure to antimicrobials. The metabolic "escape pathways" may also be neutralized by new drugs to shorten the long-term duration of therapy. Around 2 million people in the world die every year due to tuberculosis. The long-term treatment regimen could also lead to poor compliance and cause drug-resistant germs.
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