Occult Blood Test or Fecal Occult Blood Test (FOBT)
Faecal occult blood (FOB) refers to blood in the faeces that is not visibly apparent (occult). A number of conditions cause bleeding in the digestive system. Common conditions include - Colorectal cancer (cancer in the parts of the digestive system like colon, rectum) and stomach cancer. Other conditions are like peptic ulcer disease and inflammatory conditions like diverticulits and ulcerative colitis. Sometimes bleeding gums can also cause positive test and one should avoid vigorous brushing before taking such tests. Early diagnosis facilitates early intervention.
Intensive exercise or marathon running can also be the cause of low intensity GI bleeding.
Food restrictions before taking test - certain food should be avoided and these include - red meat, broccoli, turnips, and horseradish, Avoid these foods for at least 3 to 4 days before taking the test.
Drugs to avoid - colchicines, anti-coagulants such as aspirin, clopilet and oxidizing drugs (like iodine and boric acid) may make the test appear positive. Avoid vitamin C tablets too as these may interfere with the chemical reaction.
Sample collection - Ideally more than one sample over different days should be collected. Sample can be collected in a container or transferred to it using a spatula or a brush.
Microscopic examination of stools may reveal the presence of worm larvae or eggs. This can aid in the diagnosis of a number of conditions like Ascariasis, Hookworm, Strongyloidiasis and Whipworm (all of these are diseases caused by parasites).
In cases where direct examination has not helped with diagnoses, stool culture is performed. Bacterial disease can be identified by culture tests. Toxins produced by bacteria (e.g. Clostridium difficile) can be identified.
Medical conditions like lactose intolerance, infections etc. alter the pH of stool. A faecal pH may be performed. Faecal fat test can diagnose conditions causing malabsorption of fat (steatorrhea). Diseases of pancreas may be diagnosed by tests that measure faecal Elastase (an enzyme) levels.
Latest Publications and Research on Stool TestDisposition of the New Potent Acetylcholinesterase Inhibitor 8-[3-[1-[(3-fluorophenyl)methyl]-4-piperidiny]-1-oxopropyl]-1, 2, 5, 6-tetrahydro-4H-pyrrolo [3, 2, 1-ij] quinolin-4-one (TAK-802) in Rats, Dogs and Monkeys. - Published by PubMed
New Endemic Foci of Schistosomiasis Infections in the Philippines. - Published by PubMed
Helicobacter pylori and autoimmune diseases. - Published by PubMed
Is an individual calving pen better than a group calving pen for preventing transmission of Mycobacterium avium subsp paratuberculosis in calves? Results from a field trial. - Published by PubMed
Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis (PTB) in children. - Published by PubMed
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