Side effect(s) of Eliglustat

Read the side effects of Eliglustat as described in the medical literature. In case of any doubt consult your doctor or pharmacist.
Gastrointestinal: Nausea, diarrhea, gastroesophageal reflux, dyspepsia (acidity), upper abdominal pain, constipation

Nervous system: Headache, migraine

Cardiovascular: Palpitations (noticeable rapid heartbeat)

Respiratory: Oropharyngeal pain

Skin: Rash

Others: Dizziness, pain in the limbs, back pain

Lab abnormalities: ECG changes should be monitored regularly.

Other Precautions : Caution is needed while using eliglustat by pregnant women. It should be taken only if benefits are more than risks.
Pregnancy may increase the existing Gaucher disease type 1 symptoms or result in new disease manifestations. But usage of eliglustat has been found to cause reduced fetal body weight, fetal brain and skeletal abnormalities in animals.
Caution is exercised while using eliglustat by breastfeeding women.
Patients with severe kidney damage are recommended not to take eliglustat.
Eliglustat is also not recommended in all stages of liver damage.
In case of over-dosage of eliglustat, patients may experience symptoms like dizziness, disequilibrium, hypotension, low heart rate, nausea, and vomiting.
The patient should be monitored properly and given symptomatic and supportive treatment. Hemodialysis is not beneficial as eliglustat has a large volume of distribution.
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