How to Take Caplacizumab-yhdp and it's Dose

Last Updated on Nov 08, 2024

Caplacizumab is given by injection -into the vein or into the fat layer of skin by a health care provider.

Dosage & When it is to be taken

Caplacizumab should be administered upon the initiation of plasma exchange therapy.

The first dose should be given by a healthcare provider as a bolus( at a time) intravenous injection.

The recommended dose is as follows:
1st day: 11 mg bolus intravenous( into the vein) injection 15 minutes before plasma exchange followed by 11 mg subcutaneous injection (into the fat layer of skin) after completion of plasma exchange on day 1.

Subcutaneous injection in the abdomen once daily for 30 days after plasma exchange.

When it is not to be taken (Contraindications)

Previous severe allergic reaction to caplacizumab-yhdp.

What if you Miss a Dose of Caplacizumab-yhdp?

If a dose of Caplacizumab is missed during the plasma exchange, it should be given as soon as possible. If a dose is missed after the plasma exchange, it should be given within 12 hours of the scheduled time of administration. After 12 hours, the missed dose should be skipped and the next daily dose should be given according to the usual dosing schedule.