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How to Take Arsenic Trioxide and it's Dose


For newly diagnosed Acute Promyelocytic Leukemia (APL):
  • Induction therapy: The initial treatment to treat leukemia
    • Administer intravenously at a dose of 0.15 mg/kg daily until leukemia remission.
    • For induction therapy do not exceed more than 60 doses.
  • Consolidation treatment: To prevent leukemia recurrence
    • Start consolidation process 3-6 weeks following the end of induction therapy.
    • Administer 25 doses intravenously at a dose of 0.15 mg/kg daily for a period of up to 5 week.
    • The intravenous infusion is generally administered for 1-2 hours; it may be extended up to 4 hours if side effects are observed. (2 Trusted Source
      Trisenox

      Go to source
      )

When it is not to be taken (Contraindications)

  • Contraindicated in patients with known hypersensitivity to arsenic trioxide.
  • It is contraindicated in pregnant and nursing women as it may cause harmful effects on the baby.
  • Patients with liver and kidney ailments.
  • Patients with severe heart conditions.
  • Patients with heart rhythm disorders, particularly Long QT syndrome.

What if you Miss a Dose of Arsenic Trioxide?

It is important to administer doses as per the dosing schedule.
If you missed a dose, consult with your doctor for a new dosing schedule.

Drug Name : Arsenic Trioxide

In the treatment of acute promyelocytic leukemia, arsenic trioxide has been known to display strong anti-tumor effects with few toxic effects.


Trade Names/Brand Names of Arsenic Trioxide

India :


International :


Trisenox
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